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NLRX1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1271983 NLRX1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NLRX1, cDNA Clone

★Popular Item★
 Also Known As   

NLRX1 cDNA Clone

 Product Gene Name   

NLRX1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctgctg ctgggtccca cctcctcttt gtgctccatg gcttagagca tctcaacctc gacttccggc tggcaggcac gggactttgt agtgacccgg aggaaccgca ggaaccagct gctatcatcg tcaacctgct gcgcaaatac atgctgcctc aggccagcat tctggtgacc actcggccct ctgccattgg ccgtatcccc agcaagtacg tgggccgcta tggtgagatc tgcggtttct ctgataccaa cctgcagaag ctctacttcc agctccgcct caaccagccg tactgcgggt atgccgttgg cggttcaggt gtctctgcca caccagctca gcgtgaccac ctggtgcaga tgctctcccg gaacctggag gggcaccacc agatagccgc tgcctgcttc ctgccgtcct attgctggct cgtttgtgcc accttgcact tcctgcatgc ccccacgcct gctgggcaga cccttacaag catctatacc agcttcctgc gcctcaactt cagcggggaa accctggaca gcactgaccc ctccaatttg tccctgatgg cctatgcagc ccgaaccatg ggcaagttgg cctatgaggg ggtgtcctcc cgcaagacct acttctctga agaggatgtc tgtggctgcc tggaggctgg catcaggacg gaggaggagt ttcagctgct gcacatcttc cgtcgggatg ccctgaggtt tttcctggcc ccatgtgtgg agccagggcg tgcaggcacc ttcgtgttca ccgtgcccgc catgcaggaa tacctggctg ccctctacat tgtgctgggt ttgcgcaaga cgaccctgca aaaggtgggc aaggaagtgg ctgagctcgt gggccgtgtt ggggaggacg tcagcctggt actgggcatc atggccaagc tgctgcctct gcgggctctg cctctgctct tcaacctgat caaggtggtt ccacgagtgt ttgggcgcat ggtgggtaaa agccgggagg cggtggctca ggccatggtg ctggagatgt ttcgagagga ggactactac aacgatgatg ttctggacca gatgggcgcc agtatcctgg gcgtggaggg cccccggcgc cacccagatg agccccctga ggatgaagtc ttcgagctct tccccatgtt catggggggg cttctctctg cccacaaccg agctgtgcta gctcagcttg gctgccccat caagaacctg gatgccctgg agaatgccca ggccatcaag aagaagctgg gcaagctggg ccggcaggtg ctgcccccat cagagctcct tgaccacctc ttcttccact atgagttcca gaaccagcgc ttctccgctg aggtgctcag ctccctgcgt cagctcaacc tggcaggtgt gcgcatgaca ccagtcaagt gcacagtggt ggcagctgtg ctgggcagcg gaaggcatgc cctggatgag gtgaacttgg cctcctgcca gctagatcct gctgggctgc gcacactcct gcctgtcttc ctgcgtgccc ggaagctggg cttgcaactc aacagcctgg gccctgaggc ctgcaaggac ctccgagacc tgttgctgca tgaccagtgc caaattacca cactgcggct gtccaacaac ccgctgacgg aggcaggtgt tgccgtgcta atggaggggc tggcaggaaa cacctcagtg acgcacctgt ccctgctgca cacgggcctt ggggacgaag gcctggagct gctggctgcc cagctggacc gcaaccggca gctgcaggag ctgaacgtgg cgtacaacgg tgctggtgac acagcggccc tggccctggc cagagctgcc cgggagcacc cttccctgga actgctacag ggtgtcgcca tccagatgtg ttggaagctt cccctcctgc cttatgctca cctgtggaca ccgaggatgc cctcacattg gtgctttctc ctcatcctca tgcccccttt gccacaatgg tatgatggct tggtagcccc tcgaggcaga tgcacctga
 OMIM    611947
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NLRX1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for NLRX1. It may not necessarily be applicable to this product.
 NCBI GI #    16753263
 NCBI GeneID    79671
 NCBI Accession #    BC013199 [Other Products]
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 UniProt Secondary Accession #    Q7RTR3; Q96D51; Q9H724; A8K6Q1; B3KPK2; B3KTA2 [Other Products]
 UniProt Related Accession #    Q86UT6 [Other Products]
 Molecular Weight    101,876 Da
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 NCBI Official Full Name    Homo sapiens NLR family member X1, mRNA
 NCBI Official Synonym Full Names    NLR family member X1
 NCBI Official Symbol    NLRX1 [Similar Products]
 NCBI Official Synonym Symbols   
NOD5; NOD9; NOD26; DLNB26; CLR11.3
[Similar Products]
 NCBI Protein Information    NLR family member X1
 UniProt Protein Name    NLR family member X1
 UniProt Synonym Protein Names   
Caterpiller protein 11.3; CLR11.3; Nucleotide-binding oligomerization domain protein 26; Nucleotide-binding oligomerization domain protein 5; Nucleotide-binding oligomerization domain protein 9
 Protein Family    NLR family
 UniProt Gene Name    NLRX1 [Similar Products]
 UniProt Synonym Gene Names    NOD26; NOD5; NOD9; CLR11.3 [Similar Products]
 UniProt Entry Name    NLRX1_HUMAN
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 NCBI Summary for NLRX1    The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2013]
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 UniProt Comments for NLRX1    NLRX1: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF- Kappa-B and type 1 interferon signaling pathways, but enhances NF- Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313). Interacts with MAVS. Ubiquitously expressed. Strongest expression in mammary gland, heart and muscle. Detected in HeLa, HEK293T, THP-1, HL-60, Raji, and Jurkat cell lines. Belongs to the NLRP family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: mitochondrial outer membrane

Molecular Function: protein binding

Biological Process: negative regulation of interferon type I production
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 Research Articles on NLRX1    1. NLRX1, NLRP12 and NLRC3 negatively modulate the host immune response following virus exposure. (Review)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NLRX1 cdna cloneDiseases associated with NLRX1 cdna clone
 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Negative Regulators Of RIG-I/MDA5 Signaling Pathway antibodies  Negative Regulators Of RIG-I/MDA5 Signaling Pathway Diagram
 RIG-I-like Receptor Signaling Pathway antibodies  RIG-I-like Receptor Signaling Pathway Diagram
 RIG-I-like Receptor Signaling Pathway antibodies  RIG-I-like Receptor Signaling Pathway Diagram
 RIG-I/MDA5 Mediated Induction Of IFN-alpha/beta Pathways antibodies  RIG-I/MDA5 Mediated Induction Of IFN-alpha/beta Pathways Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with NLRX1 and Inflammation
 Necrosis Antibodies  >2 publications with NLRX1 and Necrosis
 Immune System Diseases Antibodies  >2 publications with NLRX1 and Immune System Diseases
 Drug Toxicity Antibodies  >1 publications with NLRX1 and Drug Toxicity
 Liver Diseases Antibodies  >1 publications with NLRX1 and Liver Diseases
Organs/Tissues associated with NLRX1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with NLRX1 and Blood
 Spleen Antibodies  >3 publications with NLRX1 and Spleen
 Intestine Antibodies  >3 publications with NLRX1 and Intestine
 Kidney Antibodies  >2 publications with NLRX1 and Kidney
 Bone Marrow Antibodies  >1 publications with NLRX1 and Bone Marrow
 Bone Antibodies  >1 publications with NLRX1 and Bone
 Lung Antibodies  >1 publications with NLRX1 and Lung
 Eye Antibodies  >1 publications with NLRX1 and Eye
 Nerve Antibodies  >1 publications with NLRX1 and Nerve
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