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NXF1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274751 NXF1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $285 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NXF1, cDNA Clone

★Popular Item★
 Also Known As   

NXF1 cDNA Clone

 Product Gene Name   

NXF1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcggacg aggggaagtc gtacagcgaa cacgatgatg aacgcgttaa tttccctcaa agaaagaaga aaggccgggg tcccttccgg tggaaatatg gtgaaggaaa ccgtaggtct ggaagaggcg gttctggtat tcggtcttcc cgccttgagg aagatgatgg agatgtggca atgagtgatg cccaggatgg tccccgagta cgatacaacc cctataccac ccgacctaac cgtcggggtg atacttggca tgatcgagat cgcattcatg ttactgtgcg gagagacaga gctcctccag agagaggagg ggctggcacc agccaggatg ggacctcaaa gaactggttc aagattacaa ttccttatgg cagaaagtat gacaaggcat ggctcctgag catgattcag agcaagtgca gtgtgccctt cacccctatt gagtttcact atgagaatac acgggcccag ttcttcgttg aagacgccag tactgcctct gcattgaagg ctgtcaacta taagattttg gatcgggaga accgaaggat atctatcatc atcaactctt ctgctccacc ccacactata ctgaatgaac tgaagccaga acaagtagaa cagctaaagc tgatcatgag caaacgatac gatggctccc aacaagccct tgacctcaaa ggcctccgtt cagacccaga tttggtggcc cagaacattg acgttgtcct gaatcgcaga agctgtatgg cagctaccct gaggatcatt gaagagaaca tccctgagct attgtccttg aacttgagca acaacaggct gtacaggctg gatgacatgt ctagcattgt tcagaaggca cccaacctga agatcctaaa cctttctgga aatgaattga agtctgagcg ggaattggac aagataaagg ggctgaagct agaagagctc tggctcgatg gaaactccct gtgtgacacc ttccgagacc agtccaccta catcagcgcc attcgcgaac gatttcccaa gttactacgc ctggatggcc atgagctacc cccaccaatt gcctttgatg ttgaagcccc cacgacgtta ccgccctgca agggaagcta ttttggaaca gaaaacttga agagtctggt cttgcacttc ctgcaacagt actatgcaat ttacgactct ggagaccgac aagggctcct ggatgcctac catgatgggg cctgctgttc cctgagcatt cctttcattc ctcagaaccc tgcccgaagc agcttagccg agtatttcaa ggatagcaga aatgtgaaga agcttaaaga ccctaccttg cggttccggc tgctgaagca cacgcgtctc aacgttgttg ccttcctcaa tgagttgccc aaaacccagc acgacgtcaa ttccttcgtg gtagacataa gcgcccagac aagcacattg ctgtgttttt ctgtcaatgg agtcttcaag gaagtggacg gaaagtcccg ggattctttg cgagccttca cccggacatt cattgctgtt cctgctagca attcagggct atgtattgta aatgatgagc tatttgtgcg gaatgccagt tctgaagaga tccaaagagc cttcgctatg cctgcaccca cgccttcctc cagcccggtg cccaccctct ctccagagca gcaggaaatg ttgcaagcat tctctaccca gtctggcatg aacctcgagt ggtcccagaa gtgccttcag gacaacaact gggactacac cagatctgcc caggccttca ctcatctcaa ggccaagggc gagatcccag aagtggcatt catgaagtga
 OMIM    602647
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NXF1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for NXF1. It may not necessarily be applicable to this product.
 NCBI GI #    33870301
 NCBI GeneID    10482
 NCBI Accession #    BC004904 [Other Products]
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 UniProt Secondary Accession #    Q99799; Q9UQL2; B4E269 [Other Products]
 UniProt Related Accession #    Q9UBU9 [Other Products]
 Molecular Weight    40,476 Da
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 NCBI Official Full Name    Homo sapiens nuclear RNA export factor 1, mRNA
 NCBI Official Synonym Full Names    nuclear RNA export factor 1
 NCBI Official Symbol    NXF1 [Similar Products]
 NCBI Official Synonym Symbols   
TAP; MEX67
[Similar Products]
 NCBI Protein Information    nuclear RNA export factor 1
 UniProt Protein Name    Nuclear RNA export factor 1
 UniProt Synonym Protein Names   
Tip-associated protein; Tip-associating protein; mRNA export factor TAP
 Protein Family    Nuclear RNA export factor
 UniProt Gene Name    NXF1 [Similar Products]
 UniProt Synonym Gene Names    TAP [Similar Products]
 UniProt Entry Name    NXF1_HUMAN
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 NCBI Summary for NXF1    This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NXF1    NXF1: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5. Belongs to the NXF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 11q12-q13

Cellular Component: cytosol; nuclear speck; nucleoplasm; nucleus

Molecular Function: protein binding; single-stranded RNA binding

Biological Process: mRNA export from nucleus; poly(A)+ mRNA export from nucleus; RNA export from nucleus
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 Research Articles on NXF1    1. Hepatitis B virus core protein associates with the cellular NXF1-p15 complex via the nuclear export signal motif of hepatitis B virus core protein.Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the NXF1-p15 machinery.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NXF1 cdna cloneDiseases associated with NXF1 cdna clone
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with NXF1 and Nervous System Diseases
 Neoplasms Antibodies  >4 publications with NXF1 and Neoplasms
 Death Antibodies  >3 publications with NXF1 and Death
 Disease Models, Animal Antibodies  >3 publications with NXF1 and Disease Models, Animal
 Aneuploidy Antibodies  >1 publications with NXF1 and Aneuploidy
 Blood Coagulation Disorders Antibodies  >1 publications with NXF1 and Blood Coagulation Disorders
 Weight Loss Antibodies  >1 publications with NXF1 and Weight Loss
 Cell Transformation, Neoplastic Antibodies  >1 publications with NXF1 and Cell Transformation, Neoplastic
Organs/Tissues associated with NXF1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with NXF1 and Brain
 Embryonic Tissue Antibodies  >3 publications with NXF1 and Embryonic Tissue
 Lymph Node Antibodies  >1 publications with NXF1 and Lymph Node
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