BC032646
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
88,435 Da
NCBI Official Full Name
Homo sapiens oxysterol binding protein-like 5, mRNA
NCBI Official Synonym Full Names
oxysterol binding protein like 5
NCBI Official Synonym Symbols
NCBI Protein Information
oxysterol-binding protein-related protein 5
UniProt Protein Name
Oxysterol-binding protein-related protein 5
UniProt Synonym Protein Names
Oxysterol-binding protein homolog 1
UniProt Synonym Gene Names
UniProt Entry Name
OSBL5_HUMAN
NCBI Summary for OSBPL5
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
UniProt Comments for OSBPL5
OSBPL5: May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Belongs to the OSBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: membrane
Molecular Function: cholesterol binding; phosphatidylserine binding; phospholipid transporter activity
Biological Process: phospholipid transport
Research Articles on OSBPL5
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Organs/Tissues associated with OSBPL5 cdna clone
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