BC000398
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,734 Da
NCBI Official Full Name
Homo sapiens platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa, mRNA
NCBI Official Synonym Full Names
platelet activating factor acetylhydrolase 1b catalytic subunit 2
NCBI Official Synonym Symbols
NCBI Protein Information
platelet-activating factor acetylhydrolase IB subunit beta
UniProt Protein Name
Platelet-activating factor acetylhydrolase IB subunit beta
UniProt Synonym Protein Names
PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta
UniProt Synonym Gene Names
UniProt Entry Name
PA1B2_HUMAN
NCBI Summary for PAFAH1B2
Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2014]
UniProt Comments for PAFAH1B2
PAFAH1B2: Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipase; EC 3.1.1.47; Acetyltransferase; Lipid Metabolism - ether lipid; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11q23
Cellular Component: cytoplasm; cytosol; nucleolus; plasma membrane
Molecular Function: phospholipase A2 activity; platelet-activating factor acetyltransferase activity
Biological Process: brain development; lipid metabolic process; positive regulation of macroautophagy
Research Articles on PAFAH1B2
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Pathways associated with PAFAH1B2 cdna clone
Diseases associated with PAFAH1B2 cdna clone
Organs/Tissues associated with PAFAH1B2 cdna clone
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