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PANX1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1277298 PANX1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PANX1, cDNA Clone

★Popular Item★
 Also Known As   

PANX1 cDNA Clone

 Product Gene Name   

PANX1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggccatcg ctcacctggc cacggagtac gtgttctcgg atttcttgct gaaggagccc acggagccca agttcaaggg gctgcgactg gagctggctg tggacaagat ggtcacgtgc attgcggtgg ggctgcccct gctgctcatc tcgctggcct tcgcgcagga gatctcgatt ggtacacaga taagctgttt ctctccaagt tctttctcct ggcgtcaggc tgcctttgtg gattcatatt gctgggcggc tgttcagcag aagaactcac tgcagagcga gtctggaaac ctcccactgt ggctgcataa gtttttcccc tacatcctgc tgctctttgc gatcctcctg tacctgcccc cgctgttctg gcgtttcgca gctgctcctc atatttgctc agacttgaag tttatcatgg aagaacttga caaagtttac aaccgtgcaa ttaaggctgc aaagagtgcg cgtgaccttg acatgagaga tggagcctgc tcagttccag gtgttaccga gaacttaggg caaagtttgt gggaggtatc tgaaagccac ttcaagtacc caattgtgga gcagtacttg aagacaaaga aaaattctaa taatttaatc atcaagtaca ttagctgccg cctgctgaca ctcatcatta tactgttagc gtgtatctac ctgggctatt acttcagcct ctcctcactc tcagacgagt ttgtgtgcag catcaaatca gggatcctga gaaacgacag caccgtgccc gatcagtttc agtgcaaact cattgccgtg ggcatcttcc agttgctcag tgtcattaac cttgtggttt atgtcctgct ggctcccgtg gttgtctaca cgctgtttgt tccattccga cagaagacag atgttctcaa agtgtacgaa atcctcccca cttttgatgt tctgcatttc aaatctgaag ggtacaacga tttgagcctc tacaatctct tcttggagga aaatataagt gaggtcaagt catacaagtg tcttaaggta ctggagaata ttaagagcag tggtcagggg atcgacccaa tgctactcct gacaaacctt ggcatgatca agatggatgt tgttgatggc aaaactccca tgtctgcaga gatgagagag gagcagggga accagacggc agagctccaa ggtatgaaca tagacagtga aactaaagca aataatggag agaagaatgc ccgacagaga cttctggatt cttcttgctg a
 OMIM    608420
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PANX1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PANX1. It may not necessarily be applicable to this product.
 NCBI GI #    16877358
 NCBI GeneID    24145
 NCBI Accession #    BC016931 [Other Products]
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 UniProt Secondary Accession #    O75968; Q543A0; Q6UW26; Q96AM9; Q96L77; Q96RS5 [Other Products]
 UniProt Related Accession #    Q96RD7 [Other Products]
 Molecular Weight    47,635 Da
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 NCBI Official Full Name    Homo sapiens pannexin 1, mRNA
 NCBI Official Synonym Full Names    pannexin 1
 NCBI Official Symbol    PANX1 [Similar Products]
 NCBI Official Synonym Symbols   
PX1; MRS1; UNQ2529
[Similar Products]
 NCBI Protein Information    pannexin-1
 UniProt Protein Name    Pannexin-1
 Protein Family    Pannexin
 UniProt Gene Name    PANX1 [Similar Products]
 UniProt Synonym Gene Names    MRS1 [Similar Products]
 UniProt Entry Name    PANX1_HUMAN
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 NCBI Summary for PANX1    The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PANX1    PANX1: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Belongs to the pannexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: endoplasmic reticulum; membrane; plasma membrane

Molecular Function: calcium channel activity; gap junction hemi-channel activity; leak channel activity; receptor binding

Biological Process: calcium ion transport; cation transport; cell-cell signaling; positive regulation of interleukin-1 beta secretion
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 Research Articles on PANX1    1. Decreased Panx1 function is a response to cell acidification mediated by IFN-gamma-induced up-regulation of Duox2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PANX1 cdna cloneDiseases associated with PANX1 cdna clone
 Products by Pathway  Pathway Diagram
 Electric Transmission Across Gap Junctions Pathway antibodies  Electric Transmission Across Gap Junctions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Inflammasomes Pathway antibodies  Inflammasomes Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways antibodies  Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways Diagram
 The NLRP3 Inflammasome Pathway antibodies  The NLRP3 Inflammasome Pathway Diagram
 Transmission Across Electrical Synapses Pathway antibodies  Transmission Across Electrical Synapses Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >18 publications with PANX1 and Inflammation
 Neoplasms Antibodies  >11 publications with PANX1 and Neoplasms
 Cardiovascular Diseases Antibodies  >7 publications with PANX1 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >5 publications with PANX1 and Disease Models, Animal
 Nerve Degeneration Antibodies  >4 publications with PANX1 and Nerve Degeneration
 Necrosis Antibodies  >3 publications with PANX1 and Necrosis
 Reperfusion Injury Antibodies  >3 publications with PANX1 and Reperfusion Injury
 Fatty Liver Antibodies  >2 publications with PANX1 and Fatty Liver
 Anoxia Antibodies  >2 publications with PANX1 and Anoxia
 Cell Transformation, Neoplastic Antibodies  >1 publications with PANX1 and Cell Transformation, Neoplastic
Organs/Tissues associated with PANX1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >54 publications with PANX1 and Brain
 Muscle Antibodies  >13 publications with PANX1 and Muscle
 Vascular Antibodies  >12 publications with PANX1 and Vascular
 Embryonic Tissue Antibodies  >11 publications with PANX1 and Embryonic Tissue
 Eye Antibodies  >9 publications with PANX1 and Eye
 Kidney Antibodies  >7 publications with PANX1 and Kidney
 Skin Antibodies  >4 publications with PANX1 and Skin
 Liver Antibodies  >3 publications with PANX1 and Liver
 Bone Antibodies  >3 publications with PANX1 and Bone
 Mouth Antibodies  >3 publications with PANX1 and Mouth
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