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PDLIM5 cdna clone

Scan QR to view Datasheet Catalog #    MBS1270134 PDLIM5 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PDLIM5, cDNA Clone

★Popular Item★
 Also Known As   


 Product Gene Name   

PDLIM5 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgagcaact acagtgtgtc actggttggc ccagctcctt ggggtttccg gctgcagggc ggtaaggatt tcaacatgcc tctgacaatc tctagtctaa aagatggcgg caaggcagcc caggcaaatg taagaatagg cgatgtggtt ctcagcattg atggaataaa tgcacaagga atgactcatc ttgaagccca gaataagatt aagggttgta caggctcttt gaatatgact ctgcaaagag catctgctgc acccaagcct gagccggttc ctgttcaaaa gaaaacacaa gtgacaaata accctggcac tgtgaaaatc ccacctaaac gcccaccaag aaaacacatt gtggagcgct atacagagtt ttatcatgta cccactcaca gtgatgccag caagaagaga ctgattgagg atactgaaga ctggcgtcca aggactggaa caactcaatc tcgctctttc cgaatccttg cccagatcac tgggactgaa catttgaaag aatctgaagc cgataataca aagaaggcaa aggaaaagat accccttcac gtctttagtc ccaaatacac aaaattacgt gactggcacc atgaagtttc agcacgtgct cttaacgtac agtga
 OMIM    605904
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PDLIM5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PDLIM5. It may not necessarily be applicable to this product.
 NCBI GI #    17389777
 NCBI GeneID    10611
 NCBI Accession #    BC017902 [Other Products]
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 UniProt Secondary Accession #    O60705; Q56VN4; Q5UW38; Q8WVK0; A8K6F9; D6RB78; E9PBF5 [Other Products]
 UniProt Related Accession #    Q96HC4 [Other Products]
 Molecular Weight    52,645 Da
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 NCBI Official Full Name    Homo sapiens PDZ and LIM domain 5, mRNA
 NCBI Official Synonym Full Names    PDZ and LIM domain 5
 NCBI Official Symbol    PDLIM5 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    PDZ and LIM domain protein 5
 UniProt Protein Name    PDZ and LIM domain protein 5
 UniProt Synonym Protein Names   
Enigma homolog; Enigma-like PDZ and LIM domains protein
 Protein Family    PDZ and LIM domain protein
 UniProt Gene Name    PDLIM5 [Similar Products]
 UniProt Synonym Gene Names    ENH [Similar Products]
 UniProt Entry Name    PDLI5_HUMAN
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 NCBI Summary for PDLIM5    This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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 UniProt Comments for PDLIM5    LIM: an adaptor protein of the Enigma family. Contains three LIM domains and one PDZ domain. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. Enigma family proteins possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4q22

Cellular Component: actin cytoskeleton; cell-cell adherens junction; cytosol; membrane; postsynaptic density

Molecular Function: actin binding; actinin binding; protein binding; protein kinase C binding

Biological Process: regulation of synaptogenesis
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 Research Articles on PDLIM5    1. It can be deduced that the nonsynonymous rs7690296 polymorphism of PDLIM5 could play an important role in the pathophysiology of both bipolar disorder and schizophrenia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PDLIM5 cdna cloneOrgans/Tissues associated with PDLIM5 cdna clone
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with PDLIM5 and Neoplasms
 Carcinoma Antibodies  >3 publications with PDLIM5 and Carcinoma
 Cardiovascular Diseases Antibodies  >2 publications with PDLIM5 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >1 publications with PDLIM5 and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >1 publications with PDLIM5 and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >1 publications with PDLIM5 and Lung Neoplasms
 Nervous System Diseases Antibodies  >1 publications with PDLIM5 and Nervous System Diseases
 Heart Diseases Antibodies  >1 publications with PDLIM5 and Heart Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with PDLIM5 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with PDLIM5 and Brain
 Heart Antibodies  >2 publications with PDLIM5 and Heart
 Prostate Antibodies  >2 publications with PDLIM5 and Prostate
 Lung Antibodies  >1 publications with PDLIM5 and Lung
 Uncharacterized Tissue Antibodies  >1 publications with PDLIM5 and Uncharacterized Tissue
 Thyroid Antibodies  >1 publications with PDLIM5 and Thyroid
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