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PNPLA8 cdna clone

Scan QR to view Datasheet Catalog #    MBS1277307 PNPLA8 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PNPLA8, cDNA Clone

 Also Known As   

PNPLA8 cDNA Clone

 Product Gene Name   

PNPLA8 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgtctatta atctgactgt agatatatat atttacctcc ttagtaatgc aagaagtgtt tgtgggaagc agagaagcaa gcaactgtat ttcttgttct cacctaagca ttactggagg ataagccaca tcagtctaca aagaggtttt catacaaaca taataagatg taaatggacc aaaagtgaag cacattcttg cagtaagcac tgttactctc caagcaacca tggtttacat attgggattt tgaaacttag cacttctgct cccaagggac ttacaaaagt gaacatttgt atgtcccgta ttaaaagtac tttgaactct gtttcaaagg ctgtttttgg caatcaaaat gaaatgattt cacgtttagc tcaatttaag ccaagttccc aaattttaag aaaagtatcg gatagtggct ggttaaaaca gaaaaacatc aaacaagcca tcaaatctct gaaaaaatat agtgacaaat cagcagaaaa gagtcctttt ccagaagaga aaagtcacat tatagacaaa gaagaagata taggtaaacg cagtcttttt cattacacaa gttctataac cacaaaattt ggagactcat tctacttttt atcaaatcat attaattcat atttcaaacg taaggaaaaa atgtctcaac aaaaggaaaa tgaacatttc cgggacaaat cagaacttga agataaaaag gtagaagagg ggaaattaag atctccagat cctggcatcc tggcttataa gccaggctca gaatctgtac atacggtgga caagcctaca agtccttctg cgatacctga tgttcttcaa gtttcaacta aacaaagtat tgctaacttt ctttctcgtc ccacggaagg tgtacaagct ttagtaggtg gttatattgg tggacttgtc cccaaattaa agtatgattc aaagagtcag tcagaagaac aggaagagcc tgctaaaact gatcaggctg tcagcaaaga cagaaatgca gaggagaaaa agcgtttatc tcttcagcga gaaaagatta tcgcaagggt gagtattgat aacaggaccc gggcattagt tcaggcatta agaagaacaa ctgacccaaa gctctgcatt actagggttg aagaactgac ttttcatctt ctagaatttc ctgaaggaaa aggagtggct gtcaaggaaa gaattattcc atatttatta cgactgagac aaattaagga tgaaactctt caggctgcag ttagagaaat tttggcccta attggctatg tggatccagt gaaagggaga ggaatccgaa ttctctcaat tgatggtgga ggaacaaggg gcgtggttgc tctccagacc ctacgaaaat tagttgaact tactcagaag ccagttcatc agctctttga ttacatttgt ggtgtaagca caggtgccat attagctttc atgttggggt tgtttcatat gcccttggat gaatgtgagg aactttatcg aaaattagga tcagatgtat tttcacaaaa tgtcattgtt ggaacagtaa aaatgagttg gagccatgca ttttatgaca gtcaaacatg ggaaaacatt cttaaggata ggatgggatc tgcactgatg attgaaacag caagaaaccc cacatgtcct aaggtagctg ctgtaagtac catagtaaat agagggataa cacccaaagc ttttgtgttc agaaactatg gtcattttcc tggaatcaac tctcattatt tgggaggctg tcagtataaa atgtggcagg ccattagagc ctcatctgct gctccaggct actttgcaga atatgcattg ggaaatgatc ttcatcaaga tggaggtttg cttctgaata acccttcggc attagctatg catgagtgta aatgtctttg gccagatgtg ccgttagagt gcatagtatc cctgggcact ggacgttatg agagtgatgt gagaaacacg gtaacataca caagcttgaa aactaaactt tctaatgtta tcaacagtgc tacagataca gaagaagtcc atataatgct tgatggcctg ttacctcctg acacctattt tagattcaat cctgtaatgt gtgaaaacat acctctagat gaaagtcgaa atgaaaagct ggatcagctg cagttggaag ggttgaaata catagaaaga aatgaacaaa aaatgaaaaa agttgcaaaa atattaagtc aagaaaaaac aactctgcag aaaattaatg attggataaa attaaaaact gatatgtatg aaggacttcc attcttttca aaattgtga
 OMIM    251950
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PNPLA8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PNPLA8. It may not necessarily be applicable to this product.
 NCBI GI #    34190006
 NCBI GeneID    50640
 NCBI Accession #    BC032999 [Other Products]
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 UniProt Secondary Accession #    O95035; Q8N3I3; Q9H7T5; Q9NR17; Q9NUN2; Q9NZ79; A4D0S1; C9JZI4 [Other Products]
 UniProt Related Accession #    Q9NP80 [Other Products]
 Molecular Weight    77,031 Da
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 NCBI Official Full Name    Homo sapiens patatin-like phospholipase domain containing 8, mRNA
 NCBI Official Synonym Full Names    patatin like phospholipase domain containing 8
 NCBI Official Symbol    PNPLA8 [Similar Products]
 NCBI Official Synonym Symbols   
MMLA; IPLA2G; IPLA2-2; iPLA2gamma; PNPLA-gamma
[Similar Products]
 NCBI Protein Information    calcium-independent phospholipase A2-gamma
 UniProt Protein Name    Calcium-independent phospholipase A2-gamma
 UniProt Synonym Protein Names   
Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-gamma; PNPLA-gamma; Patatin-like phospholipase domain-containing protein 8; iPLA2-2
 Protein Family    Calcium-independent phospholipase
 UniProt Gene Name    PNPLA8 [Similar Products]
 UniProt Synonym Gene Names    IPLA22; IPLA2G; iPLA2-gamma [Similar Products]
 UniProt Entry Name    PLPL8_HUMAN
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 NCBI Summary for PNPLA8    This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]
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 UniProt Comments for PNPLA8    PNPLA8: Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phospholipase; Membrane protein, integral; Motility/polarity/chemotaxis; EC 3.1.1.5

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: endoplasmic reticulum membrane; intracellular; membrane; peroxisomal membrane; peroxisome

Molecular Function: calcium-independent phospholipase A2 activity; phospholipase A2 activity

Biological Process: arachidonic acid metabolic process; arachidonic acid secretion; cell death; fatty acid metabolic process; linoleic acid metabolic process; phosphatidylethanolamine catabolic process; prostaglandin biosynthetic process

Disease: Mitochondrial Myopathy With Lactic Acidosis
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 Research Articles on PNPLA8    1. iPLA2gamma plays an important role in in vivo Thromboxane A2 production accompanied by thrombus formation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PNPLA8 cdna cloneOrgans/Tissues associated with PNPLA8 cdna clone
 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Phospholipid Metabolism Pathway antibodies  Phospholipid Metabolism Pathway Diagram
 Phospholipases Pathway antibodies  Phospholipases Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1 publications with PNPLA8 and Heart
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