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POLR2K cdna clone

Scan QR to view Datasheet Catalog #    MBS1271511 POLR2K cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

POLR2K, cDNA Clone

★Popular Item★
 Also Known As   

POLR2K cDNA Clone

 Product Gene Name   

POLR2K cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggacaccc agaaggacgt tcaacctcca aagcagcaac caatgatata tatctgtgga gagtgtcaca cagaaaatga aataaaatct agggatccaa tcagatgcag agaatgtgga tacagaataa tgtacaagaa aaggactaaa agattggtcg tttttgatgc tcgatga
 OMIM    606033
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of POLR2K cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for POLR2K. It may not necessarily be applicable to this product.
 NCBI GI #    12654012
 NCBI GeneID    5440
 NCBI Accession #    BC000806 [Other Products]
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 UniProt Secondary Accession #    Q6IBD4 [Other Products]
 UniProt Related Accession #    P53803 [Other Products]
 Molecular Weight    7,004 Da
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 NCBI Official Full Name    Homo sapiens polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa, mRNA
 NCBI Official Synonym Full Names    RNA polymerase II subunit K
 NCBI Official Symbol    POLR2K [Similar Products]
 NCBI Official Synonym Symbols   
RPB12; RPABC4; RPB7.0; hRPB7.0; hsRPB10a; RPB10alpha; ABC10-alpha
[Similar Products]
 NCBI Protein Information    DNA-directed RNA polymerases I, II, and III subunit RPABC4
 UniProt Protein Name    DNA-directed RNA polymerases I, II, and III subunit RPABC4
 UniProt Synonym Protein Names   
ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alpha
 UniProt Gene Name    POLR2K [Similar Products]
 UniProt Synonym Gene Names    RNA polymerases I, II, and III subunit ABC4; RPB7.0 [Similar Products]
 UniProt Entry Name    RPAB4_HUMAN
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 NCBI Summary for POLR2K    This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]
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 UniProt Comments for POLR2K    POLR2K: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.

Protein type: DNA repair, damage; RNA processing

Chromosomal Location of Human Ortholog: 8q22.2

Cellular Component: cytosol; DNA-directed RNA polymerase I complex; DNA-directed RNA polymerase II, core complex; DNA-directed RNA polymerase III complex; nucleoplasm; nucleus

Molecular Function: zinc ion binding

Biological Process: fibroblast growth factor receptor signaling pathway; gene expression; mRNA capping; nuclear mRNA splicing, via spliceosome; positive regulation of gene expression, epigenetic; positive regulation of interferon type I production; positive regulation of viral transcription; regulation of transcription from RNA polymerase I promoter; RNA elongation from RNA polymerase I promoter; RNA elongation from RNA polymerase II promoter; RNA-mediated gene silencing; snRNA transcription from RNA polymerase II promoter; somatic stem cell maintenance; termination of RNA polymerase I transcription; transcription from RNA polymerase II promoter; transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair
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 Research Articles on POLR2K    1. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with POLR2K cdna cloneDiseases associated with POLR2K cdna clone
 Products by Pathway  Pathway Diagram
 Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway antibodies  Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dual Incision Reaction In TC-NER Pathway antibodies  Dual Incision Reaction In TC-NER Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Eukaryotic Transcription Initiation Pathway antibodies  Eukaryotic Transcription Initiation Pathway Diagram
 Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies  Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >1 publications with POLR2K and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with POLR2K and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with POLR2K and Liver Diseases
Organs/Tissues associated with POLR2K cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with POLR2K and Liver
 Muscle Antibodies  >1 publications with POLR2K and Muscle
 Intestine Antibodies  >1 publications with POLR2K and Intestine
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