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PRPF4 cdna clone

Scan QR to view Datasheet Catalog #    MBS1277032 PRPF4 cdna clone
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PRPF4, cDNA Clone

 Also Known As   

PRPF4 cDNA Clone

 Product Gene Name   

PRPF4 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    607795
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PRPF4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PRPF4. It may not necessarily be applicable to this product.
 NCBI GI #    33870012
 NCBI GeneID    9128
 NCBI Accession #    BC007424 [Other Products]
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 UniProt Secondary Accession #    O43445; O43864; Q5T1M8; Q96DG2; Q96IK4 [Other Products]
 UniProt Related Accession #    O43172 [Other Products]
 Molecular Weight    58,321 Da
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 NCBI Official Full Name    Homo sapiens PRP4 pre-mRNA processing factor 4 homolog (yeast), mRNA
 NCBI Official Synonym Full Names    pre-mRNA processing factor 4
 NCBI Official Symbol    PRPF4 [Similar Products]
 NCBI Official Synonym Symbols   
PRP4; RP70; HPRP4; Prp4p; HPRP4P; SNRNP60
[Similar Products]
 NCBI Protein Information    U4/U6 small nuclear ribonucleoprotein Prp4
 UniProt Protein Name    U4/U6 small nuclear ribonucleoprotein Prp4
 UniProt Synonym Protein Names   
PRP4 homolog; hPrp4; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4
 UniProt Gene Name    PRPF4 [Similar Products]
 UniProt Synonym Gene Names    PRP4; hPrp4 [Similar Products]
 UniProt Entry Name    PRP4_HUMAN
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 NCBI Summary for PRPF4    The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
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 UniProt Comments for PRPF4    PRPF4: Involved in pre-mRNA splicing. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA processing; Spliceosome

Chromosomal Location of Human Ortholog: 9q31-q33

Cellular Component: Cajal body; nuclear speck; nucleoplasm; nucleus; spliceosome; U4/U6 x U5 tri-snRNP complex

Molecular Function: protein binding; U4 snRNA binding; U6 snRNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing

Disease: Retinitis Pigmentosa 70
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 Research Articles on PRPF4    1. The p.R192H variant of PRPF4 represents a functional null allele which compromises the function of the tri-snRNP, reinforcing the notion that this spliceosomal particle is of crucial importance in the physiology of the retina.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PRPF4 cdna cloneDiseases associated with PRPF4 cdna clone
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome, U4/U6.U5 Tri-snRNP Pathway antibodies  Spliceosome, U4/U6.U5 Tri-snRNP Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with PRPF4 and Neoplasms
 Breast Neoplasms Antibodies  >1 publications with PRPF4 and Breast Neoplasms
 Drug Toxicity Antibodies  >1 publications with PRPF4 and Drug Toxicity
 Ovarian Neoplasms Antibodies  >1 publications with PRPF4 and Ovarian Neoplasms
 Ovarian Diseases Antibodies  >1 publications with PRPF4 and Ovarian Diseases
 Aneuploidy Antibodies  >1 publications with PRPF4 and Aneuploidy
Organs/Tissues associated with PRPF4 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with PRPF4 and Bone
 Mammary Gland Antibodies  >1 publications with PRPF4 and Mammary Gland
 Bone Marrow Antibodies  >1 publications with PRPF4 and Bone Marrow
 Connective Tissue Antibodies  >1 publications with PRPF4 and Connective Tissue
 Eye Antibodies  >1 publications with PRPF4 and Eye
 Lung Antibodies  >1 publications with PRPF4 and Lung
 Brain Antibodies  >1 publications with PRPF4 and Brain
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