BC069494
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,924 Da
NCBI Official Full Name
Homo sapiens protease, serine, 3, mRNA
NCBI Official Synonym Full Names
protease, serine 3
NCBI Protein Information
trypsin-3
UniProt Protein Name
Trypsin-3
UniProt Synonym Protein Names
Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV
UniProt Synonym Gene Names
UniProt Entry Name
TRY3_HUMAN
NCBI Summary for PRSS3
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]
UniProt Comments for PRSS3
trypsin 3: Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5. Belongs to the peptidase S1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Calcium-binding; EC 3.4.21.4; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p11.2
Cellular Component: extracellular region; extracellular space
Molecular Function: calcium ion binding; protein binding; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: cobalamin metabolic process; digestion; endothelial cell migration; proteolysis; zymogen activation
Research Articles on PRSS3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with PRSS3 cdna clone
Diseases associated with PRSS3 cdna clone
Organs/Tissues associated with PRSS3 cdna clone
|