BC101127
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,941 Da
NCBI Official Full Name
Homo sapiens pyroglutamylated RFamide peptide, mRNA
NCBI Official Synonym Full Names
pyroglutamylated RFamide peptide
NCBI Official Synonym Symbols
NCBI Protein Information
orexigenic neuropeptide QRFP
UniProt Protein Name
Orexigenic neuropeptide QRFP
UniProt Synonym Protein Names
P518
UniProt Entry Name
OX26_HUMAN
NCBI Summary for QRFP
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015]
UniProt Comments for QRFP
QRFP: Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland. Belongs to the RFamide neuropeptide family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 9q34.12
Cellular Component: extracellular region
Molecular Function: neuropeptide hormone activity; orexigenic neuropeptide QRFP receptor binding
Biological Process: locomotory behavior; neuropeptide signaling pathway; positive regulation of blood pressure
Research Articles on QRFP
Precautions
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Pathways associated with QRFP cdna clone
Organs/Tissues associated with QRFP cdna clone
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