BC000896
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,541 Da
NCBI Official Full Name
Homo sapiens RAB10, member RAS oncogene family, mRNA
NCBI Official Synonym Full Names
RAB10, member RAS oncogene family
NCBI Protein Information
ras-related protein Rab-10
UniProt Protein Name
Ras-related protein Rab-10
UniProt Entry Name
RAB10_HUMAN
NCBI Summary for RAB10
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]
UniProt Comments for RAB10
RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor.
Protein type: G protein, monomeric, Rab; G protein, monomeric; G protein
Chromosomal Location of Human Ortholog: 2p23.3
Cellular Component: cell-cell adherens junction; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; endosome; exocyst; focal adhesion; Golgi apparatus; intercellular junction; plasma membrane; recycling endosome; trans-Golgi network
Molecular Function: GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding
Biological Process: antigen processing and presentation; axonogenesis; cellular response to insulin stimulus; endosome transport; establishment of neuroblast polarity; Golgi to plasma membrane protein transport; Golgi to plasma membrane transport; polarized epithelial cell differentiation; vesicle-mediated transport
Research Articles on RAB10
Precautions
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Pathways associated with RAB10 cdna clone
Diseases associated with RAB10 cdna clone
Organs/Tissues associated with RAB10 cdna clone
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