BC015014
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,508 Da
NCBI Official Full Name
Homo sapiens RAB18, member RAS oncogene family, mRNA
NCBI Official Synonym Full Names
RAB18, member RAS oncogene family
NCBI Protein Information
ras-related protein Rab-18
UniProt Protein Name
Ras-related protein Rab-18
UniProt Entry Name
RAB18_HUMAN
NCBI Summary for RAB18
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for RAB18
RAB18: a small G protein that plays a role in apical endocytosis/recycling. May be involved in transport between the plasma membrane and early endosomes.
Protein type: G protein, monomeric, Rab; G protein; G protein, monomeric
Chromosomal Location of Human Ortholog: 10p12.1
Cellular Component: cytosol; endoplasmic reticulum membrane; intracellular
Molecular Function: GDP binding; protein binding
Biological Process: brain development; eye development
Disease: Warburg Micro Syndrome 3
Research Articles on RAB18
Precautions
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Diseases associated with RAB18 cdna clone
Organs/Tissues associated with RAB18 cdna clone
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