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RAB35 cdna clone

Scan QR to view Datasheet Catalog #    MBS1267265 RAB35 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAB35, cDNA Clone

★Popular Item★
 Also Known As   

RAB35 cDNA Clone

 Product Gene Name   

RAB35 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcccggg actacgacca cctcttcaag ctgctcatca tcggcgacag cggtgtgggc aagagcagtt tactgttgcg ttttgcagac aacactttct caggcagcta catcaccacg atcggagtgg atttcaagat ccggaccgtg gagatcaacg gggagaaggt gaagctgcag atctgggaca cagcggggca ggagcgcttc cgcaccatca cctccacgta ttatcggggg acccacgggg tcattgtggt ttacgacgtc accagtgccg agtcctttgt caacgtcaag cggtggcttc acgaaatcaa ccagaactgt gatgatgtgt gccgaatatt agtgggtaat aagaatgacg accctgagcg gaaggtggtg gagacggaag atgcctacaa attcgccggg cagatgggca tccagttgtt cgagaccagc gccaaggaga atgtcaacgt ggaagagatg ttcaactgca tcacggagct ggtcctccga gcaaagaaag acaacctggc aaaacagcag cagcaacaac agaacgatgt ggtgaagctc acgaagaaca gtaaacgaaa gaaacgctgc tgctaa
 OMIM    604199
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RAB35 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for RAB35. It may not necessarily be applicable to this product.
 NCBI GI #    34190671
 NCBI GeneID    11021
 NCBI Accession #    BC015931 [Other Products]
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 UniProt Secondary Accession #    B2R6E0; B4E390 [Other Products]
 UniProt Related Accession #    Q15286 [Other Products]
 Molecular Weight    17,058 Da
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 NCBI Official Full Name    Homo sapiens RAB35, member RAS oncogene family, mRNA
 NCBI Official Synonym Full Names    RAB35, member RAS oncogene family
 NCBI Official Symbol    RAB35 [Similar Products]
 NCBI Official Synonym Symbols   
RAY; H-ray; RAB1C
[Similar Products]
 NCBI Protein Information    ras-related protein Rab-35
 UniProt Protein Name    Ras-related protein Rab-35
 UniProt Synonym Protein Names   
GTP-binding protein RAY; Ras-related protein Rab-1C
 Protein Family    Ras-related protein
 UniProt Gene Name    RAB35 [Similar Products]
 UniProt Synonym Gene Names    RAB1C; RAY [Similar Products]
 UniProt Entry Name    RAB35_HUMAN
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 UniProt Comments for RAB35    RAB35: In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. Interacts with DENND1A and DENND1B in a nucleotide- dependent manner. The low binding to DENND1C is nucleotide- independent. All 3 DENND1 act as GEFs for RAB35 and thus activate the protein. Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein; G protein, monomeric, Rab; G protein, monomeric

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cell projection membrane; clathrin-coated endocytic vesicle; coated pit; endoplasmic reticulum membrane; endosome membrane; Golgi membrane; intercellular bridge; plasma membrane

Molecular Function: GDP binding; GTP binding; GTPase activity; phosphatidylinositol-4,5-bisphosphate binding; protein binding

Biological Process: antigen processing and presentation; cytokinesis; endocytic recycling; endosome transport; ER to Golgi vesicle-mediated transport; neurite development; plasma membrane to endosome transport; protein localization
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 Research Articles on RAB35    1. Rab35 serves as a clathrin-mediated endocytosis detector. Loss of Rab35 input leads to elevated Arf6-GTP and shifts the sorting of clathrin-independent endocytosis cargo proteins to lysosomes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with RAB35 cdna cloneOrgans/Tissues associated with RAB35 cdna clone
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with RAB35 and Neoplasms
 Congenital Abnormalities Antibodies  >2 publications with RAB35 and Congenital Abnormalities
 Gonadal Disorders Antibodies  >1 publications with RAB35 and Gonadal Disorders
 Cysts Antibodies  >1 publications with RAB35 and Cysts
 Kidney Diseases Antibodies  >1 publications with RAB35 and Kidney Diseases
 Nervous System Malformations Antibodies  >1 publications with RAB35 and Nervous System Malformations
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >3 publications with RAB35 and Nerve
 Blood Antibodies  >2 publications with RAB35 and Blood
 Muscle Antibodies  >1 publications with RAB35 and Muscle
 Skin Antibodies  >1 publications with RAB35 and Skin
 Kidney Antibodies  >1 publications with RAB35 and Kidney
 Lung Antibodies  >1 publications with RAB35 and Lung
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