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RNPS1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1269932 RNPS1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNPS1, cDNA Clone

★Popular Item★
 Also Known As   

RNPS1 cDNA Clone

 Product Gene Name   

RNPS1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggatttat caggagtgaa aaagaagagc ttgctaggag tcaaagaaaa taataaaaag tccagcacta gggctccttc acctaccaaa cgcaaagacc gctcagatga gaagtccaag gatcgctcaa aagataaagg ggccaccaag gagtcgagtg agaaggatcg cggccgggac aaaacccgaa agaggcgcag cgcttccagt ggtagcagca gtaccaggtc tcggtccagc tcgacttcca gctcaggctc cagcaccagc actggctcaa gcagtggctc cagctcttcc tcagcatcca gccgctcagg aagctccagc acctcccgca gctccagctc tagcagctct tctggctctc caagtccttc tcggcgcaga cacgacaaca ggaggcgctc ccgctccaaa tccaaaccac ctaaaagaga tgaaaaggag aggaaaaggc ggagcccatc tcctaagccc accaaagtgc acattgggag actcacccgg aatgtgacaa aggatcacat catggagata ttttccacct atgggaaaat taaaatgatt gacatgcccg tggaaaggat gcatccccat ctgtccaaag gctatgcgta cgtagagttt gagaatccag atgaagccga gaaggcgctg aagcacatgg atggaggaca aattgatggc caggagatca ctgccaccgc cgtgctggcc ccctggccta ggccaccccc caggagattc agccctccca ggagaatgtt gccaccaccg cctatgtggc gcaggtctcc cccacggatg aggagaaggt cccgctcccc gaggcgcagg tcccccgtgc gccggagatc acggtccccg ggccgccgcc gccacaggag ccgctccagc tccaactcct cccgataa
 OMIM    606447
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RNPS1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for RNPS1. It may not necessarily be applicable to this product.
 NCBI GI #    33990690
 NCBI GeneID    10921
 NCBI Accession #    BC001659 [Other Products]
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 UniProt Secondary Accession #    O75308; Q32P25; Q8WY42; Q9NYG3; A8K1P0; B4DDU8; B4DZU7; B7ZA17 [Other Products]
 UniProt Related Accession #    Q15287 [Other Products]
 Molecular Weight    30,354 Da
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 NCBI Official Full Name    Homo sapiens RNA binding protein S1, serine-rich domain, mRNA
 NCBI Official Synonym Full Names    RNA binding protein with serine rich domain 1
 NCBI Official Symbol    RNPS1 [Similar Products]
 NCBI Official Synonym Symbols   
E5.1
[Similar Products]
 NCBI Protein Information    RNA-binding protein with serine-rich domain 1
 UniProt Protein Name    RNA-binding protein with serine-rich domain 1
 UniProt Synonym Protein Names   
SR-related protein LDC2
 Protein Family    RNA-binding protein with serine-rich domain
 UniProt Gene Name    RNPS1 [Similar Products]
 UniProt Synonym Gene Names    LDC2 [Similar Products]
 UniProt Entry Name    RNPS1_HUMAN
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 NCBI Summary for RNPS1    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
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 UniProt Comments for RNPS1    RNPS1: a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues.

Protein type: RNA processing; Spliceosome; RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: mRNA 3'-UTR binding; protein binding; RNA binding

Biological Process: mRNA 3'-end processing; mRNA catabolic process, nonsense-mediated decay; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; nuclear mRNA splicing, via spliceosome; positive regulation of apoptosis; regulation of alternative nuclear mRNA splicing, via spliceosome; RNA export from nucleus; RNA splicing; termination of RNA polymerase II transcription; transcription, DNA-dependent
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 Research Articles on RNPS1    1. SRBD1 gene polymorphism is associated with the development of HTG as well as NTG, including late-onset NTG.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RNPS1 cdna cloneDiseases associated with RNPS1 cdna clone
 Products by Pathway  Pathway Diagram
 Cleavage Of Growing Transcript In The Termination Region Pathway antibodies  Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
 Exon Junction Complex (EJC) Pathway antibodies  Exon Junction Complex (EJC) Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Nonsense Mediated Decay Enhanced By The Exon Junction Complex Pathway antibodies  Nonsense Mediated Decay Enhanced By The Exon Junction Complex Pathway Diagram
 Nonsense-Mediated Decay Pathway antibodies  Nonsense-Mediated Decay Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 RNA Polymerase II Transcription Pathway antibodies  RNA Polymerase II Transcription Pathway Diagram
 RNA Polymerase II Transcription Termination Pathway antibodies  RNA Polymerase II Transcription Termination Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with RNPS1 and Neoplasms
 Drug Toxicity Antibodies  >1 publications with RNPS1 and Drug Toxicity
Organs/Tissues associated with RNPS1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with RNPS1 and Bone
 Blood Antibodies  >1 publications with RNPS1 and Blood
 Ovary Antibodies  >1 publications with RNPS1 and Ovary
 Eye Antibodies  >1 publications with RNPS1 and Eye
 Liver Antibodies  >1 publications with RNPS1 and Liver
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