Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow cDNA Clone rightarrow SDHC  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • N-Methyl-D-Aspartate Receptor 1 (NMDA-R1) ELISA Kit
 • ASC Antibody
 • Treponema pallidum (TpN47) Antigen
 • 40S ribosomal protein S19 (RPS19) Recombinant Protein
 • Myoglobin (MB) ELISA Kit
 • NDRG1 cDNA Clone
 • PIP5K1A Antibody
 • USP37 Antibody
 • CCNE1-Cyclin-E1 Antibody
 • methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) (MCCC1) ELISA Kit
 • Troponin T (Tn-T) Protein
 • PAH cDNA Clone
 • solute carrier family 19 (folate transporter) , member 1 (Sl... ELISA Kit
 • TRAF2 cDNA Clone
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

SDHC cdna clone

Scan QR to view Datasheet Catalog #    MBS1270166 SDHC cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SDHC, cDNA Clone

 Also Known As   

SDHC cDNA Clone

 Product Gene Name   

SDHC cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctgcgc tgttgctgag acacgttggt cgtcattgcc tccgagccca ctttagccct cagctctgta tcagaaatgc tgttcctttg ggaaccacgg ccaaagaaga gatggagcgg ttctggaata agaatatagg ttcaaaccgt cctctgtctc cccacattac tatctacagt tggtctcttc ccatggcgat gtccatctgc caccgtggca ctggtattgc tttgagtgca ggggtctctc tttttggcat gtcggccctg ttactccctg ggaactttga gtcttatttg gaacttgtga agtccctgtg tctggggcca gcactgatcc acacagctaa gtttgcactt gtcttccctc tcatgtatca tacctggaat gggatccgac acttgatgtg ggacctagga aaaggcctga agattcccca gctataccag tctggagtgg ttgtcctggt tcttactgtg ttgtcctcta tggggctggc agccatgtga
 OMIM    602413
Section Bar
Section Bar
Section Bar
 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SDHC cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for SDHC. It may not necessarily be applicable to this product.
 NCBI GI #    21707999
 NCBI GeneID    6391
 NCBI Accession #    BC033626 [Other Products]
Section Bar
 UniProt Secondary Accession #    O75609; Q3C259; Q3C2D8; Q3C2H4; Q5VTH3 [Other Products]
 UniProt Related Accession #    Q99643 [Other Products]
 Molecular Weight    12,474 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa, mRNA
 NCBI Official Synonym Full Names    succinate dehydrogenase complex subunit C
 NCBI Official Symbol    SDHC [Similar Products]
 NCBI Official Synonym Symbols   
CYBL; PGL3; QPS1; SDH3; CYB560
[Similar Products]
 NCBI Protein Information    succinate dehydrogenase cytochrome b560 subunit, mitochondrial
 UniProt Protein Name    Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
 UniProt Synonym Protein Names   
Integral membrane protein CII-3; QPs-1; QPs1; Succinate dehydrogenase complex subunit C; Succinate-ubiquinone oxidoreductase cytochrome B large subunit; CYBL
 Protein Family    Succinate dehydrogenase 2 membrane
 UniProt Gene Name    SDHC [Similar Products]
 UniProt Synonym Gene Names    CYB560; SDH3; QPs1; CYBL [Similar Products]
 UniProt Entry Name    C560_HUMAN
Section Bar
 NCBI Summary for SDHC    This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013]
Section Bar
 UniProt Comments for SDHC    SDHC: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Defects in SDHC are the cause of paragangliomas type 3 (PGL3). A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion. Paragangliomas are most commonly located in the head and neck region, specifically at the carotid bifurcation, the jugular foramen, the vagal nerve, and in the middle ear. Defects in SDHC are a cause of paraganglioma and gastric stromal sarcoma (PGGSS); also known as Carney- Stratakis syndrome. Gastrointestinal stromal tumors may be sporadic or inherited in an autosomal dominant manner, alone or as a component of a syndrome associated with other tumors, such as in the context of neurofibromatosis type 1 (NF1). Patients have both gastrointestinal stromal tumors and paragangliomas. Susceptibility to the tumors was inherited in an apparently autosomal dominant manner, with incomplete penetrance. Belongs to the cytochrome b560 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex II; mitochondrion

Molecular Function: heme binding

Biological Process: aerobic respiration; mitochondrial electron transport, succinate to ubiquinone; tricarboxylic acid cycle

Disease: Gastrointestinal Stromal Tumor; Paraganglioma And Gastric Stromal Sarcoma; Paragangliomas 3
Table BarTOPTable Bar
 Research Articles on SDHC    1. Loss of the SDHC gene is associated with metastatic sympathetic paraganglioma.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with SDHC cdna cloneDiseases associated with SDHC cdna clone
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
 Citric Acid Cycle (TCA Cycle) Pathway antibodies  Citric Acid Cycle (TCA Cycle) Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Disease Name  Pubmed Publications
 Paraganglioma Antibodies  >203 publications with SDHC and Paraganglioma
 Neoplasms Antibodies  >196 publications with SDHC and Neoplasms
 Nervous System Diseases Antibodies  >24 publications with SDHC and Nervous System Diseases
 Carney-Stratakis Syndrome Antibodies  >11 publications with SDHC and Carney-Stratakis Syndrome
 Kidney Diseases Antibodies  >6 publications with SDHC and Kidney Diseases
 Cell Transformation, Neoplastic Antibodies  >5 publications with SDHC and Cell Transformation, Neoplastic
 Hemorrhage Antibodies  >2 publications with SDHC and Hemorrhage
 Liver Neoplasms Antibodies  >2 publications with SDHC and Liver Neoplasms
 Hypertrophy Antibodies  >1 publications with SDHC and Hypertrophy
 Fibrosis Antibodies  >1 publications with SDHC and Fibrosis
Organs/Tissues associated with SDHC cdna clone
 Organ/Tissue Name  Pubmed Publications
 Adrenal Gland Antibodies  >74 publications with SDHC and Adrenal Gland
 Blood Antibodies  >22 publications with SDHC and Blood
 Vascular Antibodies  >19 publications with SDHC and Vascular
 Thyroid Antibodies  >16 publications with SDHC and Thyroid
 Kidney Antibodies  >11 publications with SDHC and Kidney
 Bone Antibodies  >7 publications with SDHC and Bone
 Heart Antibodies  >7 publications with SDHC and Heart
 Lung Antibodies  >7 publications with SDHC and Lung
 Liver Antibodies  >5 publications with SDHC and Liver
 Brain Antibodies  >5 publications with SDHC and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions