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SORBS2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1271733 SORBS2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $285 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SORBS2, cDNA Clone

★Popular Item★
 Also Known As   

SORBS2 cDNA Clone

 Product Gene Name   

SORBS2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgagttact atcagaggcc gttttccccc tcggcatatt ctctcccagc ctcactcaac tccagcattg tcatgcagca cggcacatcc ctcgattcca cagacacata tccccagcat gcgcagtctc tggatggcac caccagcagc tctatccccc tgtaccgatc ctcagaggaa gagaagagag tgacagtcat caaagccccg cattacccag ggatcgggcc cgtggatgaa tccggaatcc ccacagcaat tagaacgaca gtcgaccggc ccaaggactg gtacaagacg atgtttaagc aaattcacat ggtgcacaag ccggatgatg acacagacat gtataatact ccttatacat acaatgcagg tctgtacaac ccaccctaca gtgctcagtc acaccctgct gcaaagaccc aaacctacag acctctttcc aaaagccact ccgacaacag ccccaatgcc tttaaggatg cgtcctcccc agtgcctccc ccacatgttc cacctccagt cccgccgctt cgaccaagag atcggtcttc aacagaaaag catgactggg atcctccaga cagaaaagtg gacacaagaa aatttcggtc tgagccaagg agtatttttg aatatgaacc tggcaagtca tcaattcttc agcatgaaag accaccccct ctcccaacaa ctccgacacc tgttccaagg gaacctggcc ggaagcctct ttctagctcc cgactcggag aagtcactgg tagcccctcc cctccgcccc ggagtggcgc ccccacacca agctcgcgcg ccccggctct gtctcccacc cggcctccta aaaagcctct ggactatgtt caagatcatt cttctggtgt tttcaatgag gcctccttgt atcagtcctc tatagacaga agcctggaaa gacccatgag ttctgcaagc atggccagtg acttcaggaa gcggaggaag agcgagcctg cagtgggtcc accacggggc ttgggagatc aaagtgcgag caggactagc ccaggccgag tggacctccc aggatcaagc accactctta caaagtcttt cactagctct tctccttctt ccccatcaag agcaaaagac cgtgagtccc ctagaagtta ctcatccact ttgactgaca tggggagaag tgcaccaagg gaaagaagag gaactccaga aaaagagaaa ttgcctgcaa aagctgttta tgattttaag gctcagacat ctaaggagtt gtcatttaag aaaggagata ctgtctacat cctcaggaaa attgatcaaa attggtatga gggagaacac cacgggagag tgggcatctt cccgatctca tacgtagaga aactcacacc tcctgagaaa gcacagcctg caagaccacc tccgccagcc cagcccggag aaatcggaga agctatagcc aaatacaact tcaacgcaga cacaaatgtg gagctgtcac tgagaaaggg agatagagtt attcttctta aaagagttga tcaaaactgg tatgaaggta aaatcccagg aaccaacaga caaggcatct tccctgtttc ctatgtggag gtcgtcaaga agaacacaaa aggtgctgag gactaccctg accctccaat accccacagc tattctagtg ataggattca cagcttgagc tcaaataagc cacagcgtcc tgtgtttact catgaaaata ttcaaggtgg gggggaaccg tttcaggctc tgtataacta tactcccagg aatgaagatg agctggagct cagagaaagt gatgtcattg atgtcatgga aaagtgtgat gacggctggt ttgtggggac ctcaagaaga accaaattct ttggtacttt ccccggaaac tacgtcaaga ggctgtga
 OMIM    616349
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SORBS2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SORBS2. It may not necessarily be applicable to this product.
 NCBI GI #    15341712
 NCBI GeneID    8470
 NCBI Accession #    BC011883 [Other Products]
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 UniProt Secondary Accession #    A6NEK9; B3KPQ7; B7Z1G5; B7Z3X6; C9JKV9; D3DP62; D3DP63; E9PAS5; E9PAW4; G3XAI0; H7BXR4 [Other Products]
 UniProt Related Accession #    O94875 [Other Products]
 Molecular Weight    80,966 Da
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 NCBI Official Full Name    Homo sapiens sorbin and SH3 domain containing 2, mRNA
 NCBI Official Synonym Full Names    sorbin and SH3 domain containing 2
 NCBI Official Symbol    SORBS2 [Similar Products]
 NCBI Official Synonym Symbols   
ARGBP2; PRO0618
[Similar Products]
 NCBI Protein Information    sorbin and SH3 domain-containing protein 2
 UniProt Protein Name    Sorbin and SH3 domain-containing protein 2
 UniProt Synonym Protein Names   
Arg-binding protein 2; ArgBP2; Arg/Abl-interacting protein 2; Sorbin
 Protein Family    Sorbin and SH3 domain-containing protein
 UniProt Gene Name    SORBS2 [Similar Products]
 UniProt Synonym Gene Names    ARGBP2; KIAA0777; ArgBP2 [Similar Products]
 UniProt Entry Name    SRBS2_HUMAN
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 NCBI Summary for SORBS2    Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SORBS2    ArgBP2: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q35.1

Cellular Component: actin cytoskeleton

Molecular Function: cytoskeletal adaptor activity; protein binding; structural constituent of cytoskeleton; structural constituent of muscle
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 Research Articles on SORBS2    1. ArgBP2 inhibits proliferation, migration, and invasion of gastric cancer cells.MORC2 down-regulates the ArgBP2 via histone methylation in gastric cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with SORBS2 cdna cloneOrgans/Tissues associated with SORBS2 cdna clone
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with SORBS2 and Neoplasms
 Pancreatic Neoplasms Antibodies  >3 publications with SORBS2 and Pancreatic Neoplasms
 Lymphoma Antibodies  >1 publications with SORBS2 and Lymphoma
 Neoplasm Metastasis Antibodies  >1 publications with SORBS2 and Neoplasm Metastasis
 Nervous System Diseases Antibodies  >1 publications with SORBS2 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with SORBS2 and Cell Transformation, Neoplastic
 Proteinuria Antibodies  >1 publications with SORBS2 and Proteinuria
 Kidney Diseases Antibodies  >1 publications with SORBS2 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >8 publications with SORBS2 and Muscle
 Heart Antibodies  >3 publications with SORBS2 and Heart
 Blood Antibodies  >2 publications with SORBS2 and Blood
 Brain Antibodies  >2 publications with SORBS2 and Brain
 Nerve Antibodies  >1 publications with SORBS2 and Nerve
 Thyroid Antibodies  >1 publications with SORBS2 and Thyroid
 Kidney Antibodies  >1 publications with SORBS2 and Kidney
 Embryonic Tissue Antibodies  >1 publications with SORBS2 and Embryonic Tissue
 Pancreas Antibodies  >1 publications with SORBS2 and Pancreas
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