BC003400
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,974 Da
NCBI Official Full Name
Homo sapiens TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa, mRNA
NCBI Official Synonym Full Names
TATA-box binding protein associated factor 9
NCBI Official Synonym Symbols
TAF2G; TAFII31; TAFII32; MGC:5067; TAFII-31; TAFII-32; TAFIID32; STAF31/32 [Similar Products]
NCBI Protein Information
transcription initiation factor TFIID subunit 9
UniProt Protein Name
Transcription initiation factor TFIID subunit 9
UniProt Synonym Protein Names
RNA polymerase II TBP-associated factor subunit G; STAF31/32; Transcription initiation factor TFIID 31 kDa subunit; TAFII-31; TAFII31; Transcription initiation factor TFIID 32 kDa subunit; TAFII-32; TAFII32
UniProt Synonym Gene Names
UniProt Entry Name
TAF9_HUMAN
NCBI Summary for TAF9
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. In human, TAF9 and AK6 (GeneID: 102157402) are two distinct genes that share 5' exons. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for TAF9
TAFII31: a component of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is essential for mediating regulation of RNA polymerase transcription. TAFII31 binds to p53, the basal transcription factor GTF2B, and the acidic transactivator viral protein 16 (VP16). It is a coactivator for P53.
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 5q13.2
Cellular Component: nucleoplasm; PCAF complex; transcription factor TFIID complex
Molecular Function: ATPase binding; DNA binding; histone acetyltransferase activity; p53 binding; protein binding; transcription activator binding; transcription coactivator activity
Biological Process: box C/D snoRNP assembly; negative regulation of apoptosis; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cell growth; positive regulation of transcription from RNA polymerase II promoter; protein stabilization; response to DNA damage stimulus; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter
Research Articles on TAF9
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Pathways associated with TAF9 cdna clone
Diseases associated with TAF9 cdna clone
Organs/Tissues associated with TAF9 cdna clone
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