BC069376
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,118 Da
NCBI Official Full Name
Homo sapiens taste receptor, type 2, member 13, mRNA
NCBI Official Synonym Full Names
taste 2 receptor member 13
NCBI Official Synonym Symbols
NCBI Protein Information
taste receptor type 2 member 13
UniProt Protein Name
Taste receptor type 2 member 13
UniProt Synonym Protein Names
Taste receptor family B member 3; TRB3
UniProt Synonym Gene Names
UniProt Entry Name
T2R13_HUMAN
NCBI Summary for TAS2R13
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
UniProt Comments for TAS2R13
TAS2R13: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, T2R family; Receptor, GPCR
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: integral to membrane; plasma membrane
Molecular Function: bitter taste receptor activity; taste receptor activity
Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; positive regulation of cytokinesis
Research Articles on TAS2R13
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Pathways associated with TAS2R13 cdna clone
Diseases associated with TAS2R13 cdna clone
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