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TEAD4 cdna clone

Scan QR to view Datasheet Catalog #    MBS1267011 TEAD4 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TEAD4, cDNA Clone

★Popular Item★
 Also Known As   

TEAD4 cDNA Clone

 Product Gene Name   

TEAD4 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgtatggtc ggaacgagct gattgcccgc tacatcaagc tccggacagg gaagacccgc accaggaagc aggtctccag ccacatccag gtgctggctc gtcgcaaagc tcgcgagatc caggccaagc taaaggacca ggcagctaag gacaaggccc tgcagagcat ggctgccatg tcgtctgcac agatcatctc cgccacggcc ttccacagta gcatggccct cgcccggggc cccggccgcc cagcagtctc agggttttgg caaggagctt tgccaggcca agccggaacg tcccatgatg tgaagccttt ctctcagcaa acctatgctg tccagcctcc gctgcctctg ccagggtttg agtctcctgc agggcccgcc ccatcgccct ctgcgccccc ggcaccccca tggcagggcc gcagcgtggc cagctccaag ctctggatgt tggagttctc tgccttcctg gagcagcagc aggacccgga cacgtacaac aagcacctgt tcgtgcacat tggccagtcc agcccaagct acagcgaccc ctacctcgaa gccgtggaca tccgccaaat ctatgacaaa ttcccggaga aaaagggtgg actcaaggat ctcttcgaac ggggaccctc caatgccttt tttcttgtga agttctgggc agacctcaac accaacatcg aggatgaagg cagctccttc tatggggtct ccagccagta tgagagcccc gagaacatga tcatcacctg ctccacgaag gtctgctctt tcggcaagca ggtggtggag aaagttgaga cagagtatgc tcgctatgag aatggacact actcttaccg catccaccgg tccccgctct gtgagtacat gatcaacttc atccacaagc tcaagcacct ccctgagaag tacatgatga acagcgtgct ggagaacttc accatcctgc aggtggtcac caacagagac acacaggaga ccttgctgtg cattgcctat gtctttgagg tgtcagccag tgagcacggg gctcagcacc acatctacag gctggtgaaa gaatga
 OMIM    601714
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TEAD4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TEAD4. It may not necessarily be applicable to this product.
 NCBI GI #    15930110
 NCBI GeneID    7004
 NCBI Accession #    BC015497 [Other Products]
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 UniProt Secondary Accession #    Q6MZR9; Q8NEV5; Q92883; Q96BK2; H0Y308 [Other Products]
 UniProt Related Accession #    Q15561 [Other Products]
 Molecular Weight    44,058 Da
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 NCBI Official Full Name    Homo sapiens TEA domain family member 4, mRNA
 NCBI Official Synonym Full Names    TEA domain transcription factor 4
 NCBI Official Symbol    TEAD4 [Similar Products]
 NCBI Official Synonym Symbols   
TEF3; RTEF1; TEF-3; EFTR-2; TEFR-1; TCF13L1; hRTEF-1B
[Similar Products]
 NCBI Protein Information    transcriptional enhancer factor TEF-3
 UniProt Protein Name    Transcriptional enhancer factor TEF-3
 UniProt Synonym Protein Names   
TEA domain family member 4; TEAD-4; Transcription factor 13-like 1; Transcription factor RTEF-1
 Protein Family    Transcriptional enhancer factor
 UniProt Gene Name    TEAD4 [Similar Products]
 UniProt Synonym Gene Names    RTEF1; TCF13L1; TEF3; TEAD-4 [Similar Products]
 UniProt Entry Name    TEAD4_HUMAN
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 NCBI Summary for TEAD4    This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TEAD4    TEAD4: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12p13.3-p13.2

Cellular Component: nucleoplasm

Molecular Function: protein binding; transcription factor activity

Biological Process: muscle development; positive regulation of defense response to virus by host; regulation of transcription from RNA polymerase II promoter; skeletal development; transcription initiation from RNA polymerase II promoter
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 Research Articles on TEAD4    1. TEAD4 and KLF5, in collaboration, promoted triple negative breast cancer cell proliferation and tumor growth in part by inhibiting p27 gene transcription
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TEAD4 cdna cloneDiseases associated with TEAD4 cdna clone
 Products by Pathway  Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway antibodies  YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with TEAD4 and Neoplasms
 Heart Diseases Antibodies  >4 publications with TEAD4 and Heart Diseases
 Cardiovascular Diseases Antibodies  >4 publications with TEAD4 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >3 publications with TEAD4 and Nervous System Diseases
 Hypertrophy Antibodies  >3 publications with TEAD4 and Hypertrophy
 Cardiomegaly Antibodies  >2 publications with TEAD4 and Cardiomegaly
 Fibrosis Antibodies  >2 publications with TEAD4 and Fibrosis
 Heart Failure Antibodies  >1 publications with TEAD4 and Heart Failure
 Neurobehavioral Manifestations Antibodies  >1 publications with TEAD4 and Neurobehavioral Manifestations
 Kidney Diseases Antibodies  >1 publications with TEAD4 and Kidney Diseases
Organs/Tissues associated with TEAD4 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >50 publications with TEAD4 and Muscle
 Vascular Antibodies  >12 publications with TEAD4 and Vascular
 Placenta Antibodies  >11 publications with TEAD4 and Placenta
 Embryonic Tissue Antibodies  >8 publications with TEAD4 and Embryonic Tissue
 Heart Antibodies  >8 publications with TEAD4 and Heart
 Blood Antibodies  >6 publications with TEAD4 and Blood
 Connective Tissue Antibodies  >5 publications with TEAD4 and Connective Tissue
 Eye Antibodies  >3 publications with TEAD4 and Eye
 Kidney Antibodies  >2 publications with TEAD4 and Kidney
 Bone Antibodies  >2 publications with TEAD4 and Bone
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