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TMEM59 cdna clone

Scan QR to view Datasheet Catalog #    MBS1266626 TMEM59 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TMEM59, cDNA Clone

★Popular Item★
 Also Known As   

TMEM59 cDNA Clone

 Product Gene Name   

TMEM59 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcggcgc cgaaggggag cctctgggtg aggacccaac tggggctccc gccgctgctg ctgctgacca tggccttggc cggaggttcg gggaccgctt cggctgaagc atttgactcg gtcttgggtg atacggcgtc ttgccaccgg gcctgtcagt tgacctaccc cttgcacacc taccctaagg aagaggagtt gtacgcatgt cagagaggtt gcaggctgtt ttcaatttgt cagtttgtgg atgatggaat tgacttaaat cgaactaaat tggaatgtga atctgcatgt acagaagcat attcccaatc tgatgagcaa tatgcttgcc atcttggttg ccagaatcag ctgccattcg ctgaactgag acaagaacaa cttatgtccc tgatgccaaa aatgcaccta ctctttcctc taactctggt gaggtcattc tggagtgaca tgatggactc cgcacagagc ttcataacct cttcatggac tttttatctt caagccgatg acggaaaaat agttatattc cagtctaagc cagaaatcca gtacgcacca catttggagc aggagcctac aaatttgaga gaatcatctc taagcaaaat gtcctcagat ctgcaaatga gaaattcaca agcgcacagg aattttcttg aagatggaga aagtgatggc tttttaagat gcctctctct taactctggg tggattttaa ctacaactct tgtcctctcg gtgatggtat tgctttggat ttgttgtgca actgttgcta cagctgtgga gcagtatgtt ccctctgaga agctgagtat ctatggtgac ttggagttta tgaatgaaca aaagctaaac agatatccag cttcttctct tgtggttgtt agatctaaaa ctgaagatca tgaagaagca gggcctctac ctacaaaagt gaatcttgct cattctgaaa tttaa
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TMEM59 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TMEM59. It may not necessarily be applicable to this product.
 NCBI GI #    16741047
 NCBI GeneID    9528
 NCBI Accession #    BC016374 [Other Products]
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 UniProt Secondary Accession #    O75393; Q4VBP9; Q5T705; Q96KX7; B3KQL7 [Other Products]
 UniProt Related Accession #    Q9BXS4 [Other Products]
 Molecular Weight    36,223 Da
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 NCBI Official Full Name    Homo sapiens transmembrane protein 59, mRNA
 NCBI Official Synonym Full Names    transmembrane protein 59
 NCBI Official Symbol    TMEM59 [Similar Products]
 NCBI Official Synonym Symbols   
DCF1; C1orf8; PRO195; UNQ169; HSPC001
[Similar Products]
 NCBI Protein Information    transmembrane protein 59
 UniProt Protein Name    Transmembrane protein 59
 UniProt Synonym Protein Names   
Liver membrane-bound protein
 Protein Family    Transmembrane protein
 UniProt Gene Name    TMEM59 [Similar Products]
 UniProt Synonym Gene Names    C1orf8 [Similar Products]
 UniProt Entry Name    TMM59_HUMAN
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 NCBI Summary for TMEM59    This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
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 UniProt Comments for TMEM59    TMEM59: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. Belongs to the TMEM59 family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: Golgi cis cisterna; Golgi medial cisterna; Golgi trans cisterna; late endosome; lysosome

Molecular Function: protein binding

Biological Process: positive regulation of autophagy
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 Research Articles on TMEM59    1. The TMEM59 gene identified from our discovery approach was recently implicated in amyloid-beta protein precursor post-translational processing, supporting a role for epigenetic change in LOAD pathology.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TMEM59 cdna cloneOrgans/Tissues associated with TMEM59 cdna clone
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >4 publications with TMEM59 and Brain Diseases
 Necrosis Antibodies  >1 publications with TMEM59 and Necrosis
 Kidney Diseases Antibodies  >1 publications with TMEM59 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >4 publications with TMEM59 and Nerve
 Brain Antibodies  >4 publications with TMEM59 and Brain
 Kidney Antibodies  >1 publications with TMEM59 and Kidney
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