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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TNP1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1275042 TNP1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNP1, cDNA Clone

★Popular Item★
 Also Known As   

TNP1 cDNA Clone

 Product Gene Name   

TNP1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgtcgacca gccgcaaatt aaagagtcat ggcatgagga ggagcaagag ccgatctcct cacaagggag tcaagagagg tggcagcaaa agaaaatacc gtaagggcaa cctgaaaagt aggaaacggg gcgatgacgc caatcgcaat taccgctccc acttgtga
 OMIM    190231
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TNP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TNP1. It may not necessarily be applicable to this product.
 NCBI GI #    20810481
 NCBI GeneID    7141
 NCBI Accession #    BC029516 [Other Products]
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 UniProt Related Accession #    P09430 [Other Products]
 Molecular Weight    6,424 Da
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 NCBI Official Full Name    Homo sapiens transition protein 1 (during histone to protamine replacement), mRNA
 NCBI Official Synonym Full Names    transition protein 1
 NCBI Official Symbol    TNP1 [Similar Products]
 NCBI Official Synonym Symbols   
TP1
[Similar Products]
 NCBI Protein Information    spermatid nuclear transition protein 1
 UniProt Protein Name    Spermatid nuclear transition protein 1
 Protein Family    Transposase for insertion sequence-like element
 UniProt Gene Name    TNP1 [Similar Products]
 UniProt Synonym Gene Names    STP-1; TP-1 [Similar Products]
 UniProt Entry Name    STP1_HUMAN
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 NCBI Summary for TNP1    Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for TNP1    TP1: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 1 family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: male germ cell nucleus; nucleosome

Molecular Function: DNA binding; protein binding

Biological Process: chromatin remodeling; chromatin silencing; fertilization, exchange of chromosomal proteins; negative regulation of transcription, DNA-dependent; nucleosome disassembly; sexual reproduction; single strand break repair; sperm motility; spermatid development; spermatid nuclear differentiation; spermatid nuclear elongation
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 Research Articles on TNP1    1. Among Systemic lupus erythematosus patients, 63.6% and 45.5% of those with lupus nephritis were positive for anti-RRP8 and anti-TNP1 antibodies, compared with 12.5% and 9.4% of Systemic lupus erythematosus patients without nephritis, respectively.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TNP1 cdna cloneOrgans/Tissues associated with TNP1 cdna clone
 Disease Name  Pubmed Publications
 Infertility Antibodies  >13 publications with TNP1 and Infertility
 Infertility, Female Antibodies  >3 publications with TNP1 and Infertility, Female
 Lens Diseases Antibodies  >1 publications with TNP1 and Lens Diseases
 Adenocarcinoma Antibodies  >1 publications with TNP1 and Adenocarcinoma
 Carcinoma Antibodies  >1 publications with TNP1 and Carcinoma
 Colonic Neoplasms Antibodies  >1 publications with TNP1 and Colonic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >10 publications with TNP1 and Testis
 Brain Antibodies  >1 publications with TNP1 and Brain
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