BC018117
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,853 Da
NCBI Official Full Name
Homo sapiens tumor protein D52, mRNA
NCBI Official Synonym Full Names
tumor protein D52
NCBI Protein Information
tumor protein D52
UniProt Protein Name
Tumor protein D52
UniProt Synonym Protein Names
Protein N8
UniProt Entry Name
TPD52_HUMAN
UniProt Comments for TPD52
TPD52: a coiled-coil motif bearing hydrophilic protein known to be overexpressed in many human solid tumors of diverse cellular origins. May be associated with B cell differentiation. Increased expression is associated with increased proliferation and invasive capacity in different cell types. May negatively regulate ATM protein levels. Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and heart, and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary. Isoform 2 is expressed at lower levels in fetal brain and kidney than in adult brain and kidney. Eight isoforms of the human protein are produced by alternative splicing
Protein type: Calcium-binding; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 8q21.13
Cellular Component: cytoplasm; endoplasmic reticulum; perinuclear region of cytoplasm
Molecular Function: calcium ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: anatomical structure morphogenesis; B cell differentiation; secretion
Research Articles on TPD52
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with TPD52 cdna clone
Diseases associated with TPD52 cdna clone
Organs/Tissues associated with TPD52 cdna clone
|