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TRPM1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1266236 TRPM1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TRPM1, cDNA Clone

★Popular Item★
 Also Known As   

TRPM1 cDNA Clone

 Product Gene Name   

TRPM1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgaaagact ctaacaggtg ttgctgtggc cagttcacca accagcatat cccccctctg ccaagtgcaa cacccagcaa aaatgaagag gaaaacaaac aggtggagac tcagcctgag aaatggtctg ttgccaagca cacccagagc tacccaacag attcctatgg agttcttgaa ttccagggtg gcggatattc caataaagcc atggtgagaa aggcattcag acatggtgcc actaggatca cagctttcat tggcggccag tctcccagcc ccaaactgca gatacctggt cttcttcatg gctgtggctc aatcttccta gatatttcat tgaaaaacca agagatatat ctgtgcacat ggcttttagc catgaggctt ggaaactgga caccactgta a
 OMIM    603576
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TRPM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TRPM1. It may not necessarily be applicable to this product.
 NCBI GI #    34849477
 NCBI GeneID    4308
 NCBI Accession #    BC058286 [Other Products]
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 UniProt Secondary Accession #    O75560; Q6PE48; Q7Z4N1; Q7Z4N3; Q7Z4N4; Q7Z4N5; D9IDV2; D9IDV3; F8W865; H0YN37 [Other Products]
 UniProt Related Accession #    Q7Z4N2 [Other Products]
 Molecular Weight    15,099 Da
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 NCBI Official Full Name    Homo sapiens transient receptor potential cation channel, subfamily M, member 1, mRNA
 NCBI Official Synonym Full Names    transient receptor potential cation channel subfamily M member 1
 NCBI Official Symbol    TRPM1 [Similar Products]
 NCBI Official Synonym Symbols   
MLSN1; CSNB1C; LTRPC1
[Similar Products]
 NCBI Protein Information    transient receptor potential cation channel subfamily M member 1
 UniProt Protein Name    Transient receptor potential cation channel subfamily M member 1
 UniProt Synonym Protein Names   
Long transient receptor potential channel 1; LTrpC1; Melastatin-1
 Protein Family    Transient receptor potential cation channel subfamily
 UniProt Gene Name    TRPM1 [Similar Products]
 UniProt Synonym Gene Names    LTrpC1 [Similar Products]
 UniProt Entry Name    TRPM1_HUMAN
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 NCBI Summary for TRPM1    This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
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 UniProt Comments for TRPM1    TRPM1: a transient receptor potential (TRP) ion channel. TRP voltage-independent calcium-permeable cation channels are divided into six subfamilies, two of which (TRPC and TRPM) have members that are widely expressed. Its expression is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis.

Protein type: Membrane protein, integral; Channel, calcium; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: calcium channel activity

Biological Process: metabotropic glutamate receptor signaling pathway; transport; visual perception

Disease: Night Blindness, Congenital Stationary, Type 1c
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 Research Articles on TRPM1    1. genotype-phenotype correlations showed that this eye phenotype was secondary to homozygous deletion of TRPM1, the gene responsible for autosomal recessive congenital stationary night blindness. The main differential diagnosis is ceroid lipofuscinosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TRPM1 cdna cloneOrgans/Tissues associated with TRPM1 cdna clone
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >24 publications with TRPM1 and Neoplasms
 Skin Neoplasms Antibodies  >7 publications with TRPM1 and Skin Neoplasms
 Necrosis Antibodies  >3 publications with TRPM1 and Necrosis
 Inflammation Antibodies  >2 publications with TRPM1 and Inflammation
 Brain Diseases Antibodies  >2 publications with TRPM1 and Brain Diseases
 Fibrosis Antibodies  >1 publications with TRPM1 and Fibrosis
 Hypertension Antibodies  >1 publications with TRPM1 and Hypertension
 Neurobehavioral Manifestations Antibodies  >1 publications with TRPM1 and Neurobehavioral Manifestations
 Lung Neoplasms Antibodies  >1 publications with TRPM1 and Lung Neoplasms
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with TRPM1 and Prenatal Exposure Delayed Effects
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >36 publications with TRPM1 and Eye
 Skin Antibodies  >16 publications with TRPM1 and Skin
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