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TRPV6 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274228 TRPV6 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TRPV6, cDNA Clone

★Popular Item★
 Also Known As   

TRPV6 cDNA Clone

 Product Gene Name   

TRPV6 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgtacgttg agaatcactg ctccaggcct gcattactcc ttcagctctg gggcagagga agcccagccc aagcacgggg ctggcagggc gtgaggaact ctcctgtggc ctgctcatca cccttccgac aggagcactg catgtcagag cactttaaaa acaggccagc ctgcttgggc gctcggtctc caccccaggg tcataagtgg ggagagagcc cttcccaggg cacccaggca ggtgcaggga agtgcagagc ttgtggaaag cgtgtgagtg agggagacag gaacggctct gggggtggga agtggggcta g
 OMIM    606680
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TRPV6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TRPV6. It may not necessarily be applicable to this product.
 NCBI GI #    21961317
 NCBI GeneID    55503
 NCBI Accession #    BC034814 [Other Products]
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 UniProt Secondary Accession #    Q8TDL3; Q8WXR8; Q96LC5; Q9H1D1; Q9H296; A4D2I8 [Other Products]
 UniProt Related Accession #    Q9H1D0 [Other Products]
 Molecular Weight    68,446 Da
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 NCBI Official Full Name    Homo sapiens transient receptor potential cation channel, subfamily V, member 6, mRNA
 NCBI Official Synonym Full Names    transient receptor potential cation channel subfamily V member 6
 NCBI Official Symbol    TRPV6 [Similar Products]
 NCBI Official Synonym Symbols   
CAT1; CATL; ZFAB; ECAC2; ABP/ZF; LP6728; HSA277909
[Similar Products]
 NCBI Protein Information    transient receptor potential cation channel subfamily V member 6
 UniProt Protein Name    Transient receptor potential cation channel subfamily V member 6
 UniProt Synonym Protein Names   
CaT-like; CaT-L; Calcium transport protein 1; CaT1; Epithelial calcium channel 2; ECaC2
 Protein Family    Transient receptor potential cation channel subfamily
 UniProt Gene Name    TRPV6 [Similar Products]
 UniProt Synonym Gene Names    ECAC2; TrpV6; CaT-L; CaT1; ECaC2 [Similar Products]
 UniProt Entry Name    TRPV6_HUMAN
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 NCBI Summary for TRPV6    This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]
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 UniProt Comments for TRPV6    TRPV6: Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin- dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV6 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, calcium; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: calcium channel activity; calmodulin binding; protein binding

Biological Process: calcium ion transport
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 Research Articles on TRPV6    1. TRPV6 calcium ion channel plays a critical role in flow-induced Ca(2+) influx and microvilli formation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TRPV6 cdna cloneDiseases associated with TRPV6 cdna clone
 Products by Pathway  Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Signaling Events Mediated By PTP1B Pathway antibodies  Signaling Events Mediated By PTP1B Pathway Diagram
 TCR Signaling In Naive CD4+ T Cells Pathway antibodies  TCR Signaling In Naive CD4+ T Cells Pathway Diagram
 TCR Signaling In Naive CD8+ T Cells Pathway antibodies  TCR Signaling In Naive CD8+ T Cells Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >44 publications with TRPV6 and Neoplasms
 Hypercalciuria Antibodies  >22 publications with TRPV6 and Hypercalciuria
 Prostatic Neoplasms Antibodies  >20 publications with TRPV6 and Prostatic Neoplasms
 Kidney Diseases Antibodies  >20 publications with TRPV6 and Kidney Diseases
 Hypercalcemia Antibodies  >11 publications with TRPV6 and Hypercalcemia
 Hypocalcemia Antibodies  >11 publications with TRPV6 and Hypocalcemia
 Rickets Antibodies  >10 publications with TRPV6 and Rickets
 Hypertension Antibodies  >8 publications with TRPV6 and Hypertension
 Pain Antibodies  >7 publications with TRPV6 and Pain
 Nephrolithiasis Antibodies  >5 publications with TRPV6 and Nephrolithiasis
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