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UBASH3B cdna clone

Scan QR to view Datasheet Catalog #    MBS1277810 UBASH3B cdna clone
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   


 Product Gene Name   

UBASH3B cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    609201
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of UBASH3B cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for UBASH3B. It may not necessarily be applicable to this product.
 NCBI GI #    14043110
 NCBI GeneID    84959
 NCBI Accession #    BC007541 [Other Products]
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 UniProt Secondary Accession #    Q53GT5; Q53GT8; Q8NBV7; Q96IG9; Q96NZ2 [Other Products]
 UniProt Related Accession #    Q8TF42 [Other Products]
 Molecular Weight    72,696 Da
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 NCBI Official Full Name    Homo sapiens ubiquitin associated and SH3 domain containing, B, mRNA
 NCBI Official Synonym Full Names    ubiquitin associated and SH3 domain containing B
 NCBI Official Symbol    UBASH3B [Similar Products]
 NCBI Official Synonym Symbols   
p70; STS1; STS-1; TULA2; TULA-2
[Similar Products]
 NCBI Protein Information    ubiquitin-associated and SH3 domain-containing protein B
 UniProt Protein Name    Ubiquitin-associated and SH3 domain-containing protein B
 UniProt Synonym Protein Names   
Cbl-interacting protein p70; Suppressor of T-cell receptor signaling 1; STS-1; T-cell ubiquitin ligand 2; TULA-2; Tyrosine-protein phosphatase STS1/TULA2
 Protein Family    Ubiquitin-associated and SH3 domain-containing protein
 UniProt Gene Name    UBASH3B [Similar Products]
 UniProt Synonym Gene Names    KIAA1959; STS1; STS-1; TULA-2 [Similar Products]
 UniProt Entry Name    UBS3B_HUMAN
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 NCBI Summary for UBASH3B    This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]
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 UniProt Comments for UBASH3B    STS-1: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

Protein type: Protein phosphatase, tyrosine (non-receptor); EC

Chromosomal Location of Human Ortholog: 11q24.1

Molecular Function: protein binding
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 Research Articles on UBASH3B    1. The study reveals a role of CBL in restricting myeloid proliferation of human AML1-ETOinduced leukemia, and identifies UBASH3B as a potential target for pharmaceutical intervention.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with UBASH3B cdna cloneOrgans/Tissues associated with UBASH3B cdna clone
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with UBASH3B and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with UBASH3B and Blood
 Skin Antibodies  >2 publications with UBASH3B and Skin
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