BC023286
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,658 Da
NCBI Official Full Name
Homo sapiens vesicle-associated membrane protein 1 (synaptobrevin 1), mRNA
NCBI Official Synonym Full Names
vesicle associated membrane protein 1
NCBI Protein Information
vesicle-associated membrane protein 1
UniProt Protein Name
Vesicle-associated membrane protein 1
UniProt Synonym Protein Names
Synaptobrevin-1
UniProt Synonym Gene Names
UniProt Entry Name
VAMP1_HUMAN
NCBI Summary for VAMP1
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]
UniProt Comments for VAMP1
VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p
Cellular Component: cytosol; integral to plasma membrane; SNARE complex; synaptic vesicle membrane
Molecular Function: protein binding; SNAP receptor activity; SNARE binding
Biological Process: exocytosis; vesicle fusion
Disease: Spastic Ataxia 1, Autosomal Dominant
Research Articles on VAMP1
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Pathways associated with VAMP1 cdna clone
Diseases associated with VAMP1 cdna clone
Organs/Tissues associated with VAMP1 cdna clone
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