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VAMP2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1270992 VAMP2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

VAMP2, cDNA Clone

 Also Known As   

VAMP2 cDNA Clone

 Product Gene Name   

VAMP2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgtctgcta ccgctgccac ggccccccct gctgccccgg ctggggaggg tggtccccct gcaccccctc caaacctcac cagtaacagg agactgcagc agacccaggc ccaggtggat gaggtggtgg acatcatgag ggtgaacgtg gacaaggtcc tggagcgaga ccagaagctg tcggagctgg acgaccgtgc agatgcactc caggcggggg cctcccagtt tgaaacaagc gcagccaagc tcaagcgcaa atactggtgg aaaaacctca agatgatgat catcttggga gtgatttgcg ccatcatcct catcatcatc atagtttact tcagcactta a
 OMIM    185881
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of VAMP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for VAMP2. It may not necessarily be applicable to this product.
 NCBI GI #    33877103
 NCBI GeneID    6844
 NCBI Accession #    BC002737 [Other Products]
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 UniProt Secondary Accession #    P19065; Q9BUC2 [Other Products]
 UniProt Related Accession #    P63027 [Other Products]
 Molecular Weight    12,663 Da
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 NCBI Official Full Name    Homo sapiens vesicle-associated membrane protein 2 (synaptobrevin 2), mRNA
 NCBI Official Synonym Full Names    vesicle associated membrane protein 2
 NCBI Official Symbol    VAMP2 [Similar Products]
 NCBI Official Synonym Symbols   
SYB2; VAMP-2
[Similar Products]
 NCBI Protein Information    vesicle-associated membrane protein 2
 UniProt Protein Name    Vesicle-associated membrane protein 2
 UniProt Synonym Protein Names   
Synaptobrevin-2
 Protein Family    Vesicle-associated membrane protein
 UniProt Gene Name    VAMP2 [Similar Products]
 UniProt Synonym Gene Names    SYB2; VAMP-2 [Similar Products]
 UniProt Entry Name    VAMP2_HUMAN
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 NCBI Summary for VAMP2    The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
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 UniProt Comments for VAMP2    VAMP2: a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: clathrin-coated vesicle; cytoplasmic vesicle; cytosol; integral to plasma membrane; intracellular membrane-bound organelle; membrane; neuron projection; perinuclear region of cytoplasm; plasma membrane; secretory granule; secretory granule membrane; SNARE complex; synapse; synaptic vesicle; synaptic vesicle membrane; trans-Golgi network; vesicle; voltage-gated potassium channel complex; zymogen granule membrane

Molecular Function: calcium-dependent protein binding; calmodulin binding; phospholipid binding; protein binding; protein self-association; SNAP receptor activity; SNARE binding; syntaxin binding; syntaxin-1 binding

Biological Process: calcium ion-dependent exocytosis; cellular response to insulin stimulus; eosinophil degranulation; exocytosis; glutamate secretion; Golgi to plasma membrane protein transport; natural killer cell degranulation; neurotransmitter secretion; neutrophil degranulation; post-Golgi vesicle-mediated transport; protein complex assembly; protein transport; regulation of exocytosis; response to glucose stimulus; synaptic vesicle exocytosis; vesicle fusion; vesicle-mediated transport
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 Research Articles on VAMP2    1. VAMP2-NRG1 is a novel oncogenic fusion gene representing a new addition to the list of NRG1 fusion genes, which together may form an important diagnostic and clinical category of lung adenocarcinoma cases
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with VAMP2 cdna cloneDiseases associated with VAMP2 cdna clone
 Products by Pathway  Pathway Diagram
 Acetylcholine Neurotransmitter Release Cycle Pathway antibodies  Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
 BoNT Light Chain Types B, D, And F Cleave VAMP/Synaptobrevin Pathway antibodies  BoNT Light Chain Types B, D, And F Cleave VAMP/Synaptobrevin Pathway Diagram
 Botulinum Neurotoxicity Pathway antibodies  Botulinum Neurotoxicity Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dopamine Neurotransmitter Release Cycle Pathway antibodies  Dopamine Neurotransmitter Release Cycle Pathway Diagram
 Effects Of Botulinum Toxin Pathway antibodies  Effects Of Botulinum Toxin Pathway Diagram
 GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies  GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
 Glutamate Neurotransmitter Release Cycle Pathway antibodies  Glutamate Neurotransmitter Release Cycle Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >35 publications with VAMP2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >17 publications with VAMP2 and Disease Models, Animal
 Neoplasms Antibodies  >12 publications with VAMP2 and Neoplasms
 Inflammation Antibodies  >10 publications with VAMP2 and Inflammation
 Seizures Antibodies  >5 publications with VAMP2 and Seizures
 Cardiovascular Diseases Antibodies  >5 publications with VAMP2 and Cardiovascular Diseases
 Cognition Disorders Antibodies  >5 publications with VAMP2 and Cognition Disorders
 Learning Disorders Antibodies  >4 publications with VAMP2 and Learning Disorders
 Movement Disorders Antibodies  >4 publications with VAMP2 and Movement Disorders
 Kidney Diseases Antibodies  >4 publications with VAMP2 and Kidney Diseases
Organs/Tissues associated with VAMP2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >176 publications with VAMP2 and Brain
 Nerve Antibodies  >151 publications with VAMP2 and Nerve
 Muscle Antibodies  >68 publications with VAMP2 and Muscle
 Pancreas Antibodies  >34 publications with VAMP2 and Pancreas
 Blood Antibodies  >34 publications with VAMP2 and Blood
 Kidney Antibodies  >27 publications with VAMP2 and Kidney
 Eye Antibodies  >16 publications with VAMP2 and Eye
 Embryonic Tissue Antibodies  >14 publications with VAMP2 and Embryonic Tissue
 Salivary Gland Antibodies  >11 publications with VAMP2 and Salivary Gland
 Heart Antibodies  >9 publications with VAMP2 and Heart
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