BC096729
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UniProt Related Accession #
Molecular Weight
12,917 Da
NCBI Official Full Name
Homo sapiens variable charge, Y-linked, mRNA
NCBI Official Synonym Full Names
variable charge, Y-linked
NCBI Protein Information
testis-specific basic protein Y 1
UniProt Protein Name
Testis-specific basic protein Y 1
UniProt Synonym Protein Names
Basic charge, Y-linked 1; Variably charged protein Y
UniProt Synonym Gene Names
UniProt Entry Name
VCY1_HUMAN
NCBI Summary for VCY
The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. [provided by RefSeq, Jul 2008]
UniProt Comments for VCY
VCY: May mediate a process in spermatogenesis or may play a role in sex ratio distortion. Belongs to the VCX/VCY family.
Chromosomal Location of Human Ortholog: Yq11.221
Cellular Component: nucleolus
Biological Process: brain development
Disease: Spermatogenic Failure, Y-linked, 2
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Organs/Tissues associated with VCY cdna clone
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