BC001621
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69,998 Da
NCBI Official Full Name
Homo sapiens WW domain binding protein 11, mRNA
NCBI Official Synonym Full Names
WW domain binding protein 11
NCBI Protein Information
WW domain-binding protein 11
UniProt Protein Name
WW domain-binding protein 11
UniProt Synonym Protein Names
Npw38-binding protein; NpwBP; SH3 domain-binding protein SNP70; Splicing factor that interacts with PQBP-1 and PP1
UniProt Synonym Gene Names
UniProt Entry Name
WBP11_HUMAN
NCBI Summary for WBP11
This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]
UniProt Comments for WBP11
WBP11: Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.
Protein type: Protein phosphatase, regulatory subunit; RNA processing; DNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: cytoplasm; intracellular membrane-bound organelle; nucleoplasm; nucleus; spliceosome
Molecular Function: protein binding; single-stranded DNA binding; WW domain binding
Biological Process: nuclear mRNA cis splicing, via U2-type spliceosome
Research Articles on WBP11
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Pathways associated with WBP11 cdna clone
Diseases associated with WBP11 cdna clone
Organs/Tissues associated with WBP11 cdna clone
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