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YAF2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1273948 YAF2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

YAF2, cDNA Clone

 Also Known As   

YAF2 cDNA Clone

 Product Gene Name   

YAF2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgggagaca agaagagccc caccaggccg aagcggcagc cgaagccgtc ctcggatgag ggttactggg actgtagcgt ctgcaccttc cggaacagcg ccgaggcctt caagtgcatg atgtgcgatg tgcggaaggg cacctccacc cgatccacat tgtttgaagt tattgtgagt gcctcgagga ccaaggaacc gttgaaattt ccaatttcag gaaggaaacc tcgacctgtc tcccagttgg ttgcacagca ggttactcag cagtttgtgc ctcctacaca gtcaaagaaa gagaaaaaag ataaagtaga aaaagaaaaa agtgaaaagg aaacaactag caaaaagaat agccataaga aaaccaggcc aagattgaaa aatgtggatc ggagtagtgc tcagcatttg gaagttactg ttggagatct gacagtcatt attacagact ttaaggagaa aacaaagtca ccgcctgcat ctagtgctgc ctctgcagat caacacagtc aaagcggctc tagctctgat aacacagaga gaggaatgtc caggtcatct tcacccagag gagaagcctc atcattgaat ggagaatctc attaa
 OMIM    607534
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of YAF2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for YAF2. It may not necessarily be applicable to this product.
 NCBI GI #    34191154
 NCBI GeneID    10138
 NCBI Accession #    BC037777 [Other Products]
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 UniProt Secondary Accession #    Q99710; A8K5P0; B4DFU3; G3V465 [Other Products]
 UniProt Related Accession #    Q8IY57 [Other Products]
 Molecular Weight    12,738 Da
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 NCBI Official Full Name    Homo sapiens YY1 associated factor 2, mRNA
 NCBI Official Synonym Full Names    YY1 associated factor 2
 NCBI Official Symbol    YAF2 [Similar Products]
 NCBI Protein Information    YY1-associated factor 2
 UniProt Protein Name    YY1-associated factor 2
 Protein Family    YY1-associated factor
 UniProt Gene Name    YAF2 [Similar Products]
 UniProt Entry Name    YAF2_HUMAN
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 NCBI Summary for YAF2    This gene encodes a zinc finger containing protein that functions in the regulation of transcription. This protein was identified as an interacting partner of transcriptional repressor protein Yy1, and also interacts with other transcriptional regulators, including Myc and Polycomb. This protein can promote proteolysis of Yy1. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Feb 2016]
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 UniProt Comments for YAF2    YAF2: Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity; transcription corepressor activity

Biological Process: negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent
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 Research Articles on YAF2    1. These findings uncovered an apoptotic signaling cascade linking YAF2, PDCD5, and TP53 during genotoxic stress responses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with YAF2 cdna cloneOrgans/Tissues associated with YAF2 cdna clone
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with YAF2 and Neoplasms
 Neurobehavioral Manifestations Antibodies  >1 publications with YAF2 and Neurobehavioral Manifestations
 Nervous System Diseases Antibodies  >1 publications with YAF2 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >1 publications with YAF2 and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >1 publications with YAF2 and Abnormalities, Multiple
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >9 publications with YAF2 and Muscle
 Bone Antibodies  >1 publications with YAF2 and Bone
 Nerve Antibodies  >1 publications with YAF2 and Nerve
 Ovary Antibodies  >1 publications with YAF2 and Ovary
 Heart Antibodies  >1 publications with YAF2 and Heart
 Skin Antibodies  >1 publications with YAF2 and Skin
 Placenta Antibodies  >1 publications with YAF2 and Placenta
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