BC015030
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
78,156 Da
NCBI Official Full Name
Homo sapiens zinc finger, BED-type containing 1, mRNA
NCBI Official Synonym Full Names
zinc finger BED-type containing 1
NCBI Protein Information
zinc finger BED domain-containing protein 1
UniProt Protein Name
Zinc finger BED domain-containing protein 1
UniProt Synonym Protein Names
Putative Ac-like transposable element; dREF homolog
UniProt Synonym Gene Names
UniProt Entry Name
ZBED1_HUMAN
NCBI Summary for ZBED1
This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for ZBED1
ZBED1: Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: Xp22.33;Yp11
Cellular Component: actin cytoskeleton; cytoplasm; nuclear chromosome; nucleus
Molecular Function: protein binding; transcription factor activity; transposase activity
Biological Process: regulation of transcription from RNA polymerase II promoter
Research Articles on ZBED1
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Diseases associated with ZBED1 cdna clone
Organs/Tissues associated with ZBED1 cdna clone
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