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GAD1 shrna

Scan QR to view Datasheet Catalog #    MBS8270506 GAD1 shrna
Unit / Price
  DISCONTINUED
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GAD1, shRNA

 Also Known As   

GAD1 shRNA Plasmid (Mouse)

 Product Synonym Names    GAD67; Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform
 Product Gene Name   

GAD1 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P48318
 Host    E Coli
 Species Reactivity    Mouse
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 Specificity    GAD1 shRNA Plasmid (Mouse) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down mouse GAD1 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of GAD1 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for GAD1 shrna

   shRNA Plasmid to inhibit GAD1 expression by RNA interference
 Applications Tested/Suitable for GAD1 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for GAD1. It may not necessarily be applicable to this product.
 NCBI GI #    31982847
 NCBI GeneID    14415
 NCBI Accession #    NP_032103.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008077.5 [Other Products]
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 UniProt Primary Accession #    P48318 [Other Products]
 UniProt Secondary Accession #    O08685 [Other Products]
 UniProt Related Accession #    P48318 [Other Products]
 Molecular Weight    66,648 Da
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 NCBI Official Full Name    glutamate decarboxylase 1 isoform GAD67
 NCBI Official Synonym Full Names    glutamate decarboxylase 1
 NCBI Official Symbol    Gad1 [Similar Products]
 NCBI Official Synonym Symbols   
EP10; Gad-1
[Similar Products]
 NCBI Protein Information    glutamate decarboxylase 1
 UniProt Protein Name    Glutamate decarboxylase 1
 UniProt Synonym Protein Names   
67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform
 Protein Family    Glutamate decarboxylase
 UniProt Gene Name    Gad1 [Similar Products]
 UniProt Synonym Gene Names    Gad67; GAD-67 [Similar Products]
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 NCBI Summary for GAD1    The protein encoded by this gene is an enzyme that catalyzes the production of gamma-aminobutyric acid from L-glutamic acid. Alternative splicing of this gene results in two products, the predominant 67 kDa isoform and a smaller 25 kDa isoform. The smaller isoform is not thought to retain catalytic activity. [provided by RefSeq, Aug 2015]
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 UniProt Comments for GAD1    Catalyzes the production of GABA.
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 Research Articles on GAD1    1. This study demonstrated that Alterations in hypoglossal motor neurons due to GAD67 deficiency in mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GAD1 shrnaPathways associated with GAD1 shrna
 Reference Product  PubMed Publications
 Reln shrna  >12 publications with GAD1 and Reln
 Olig2 shrna  >3 publications with GAD1 and Olig2
 Slc32a1 shrna  >2 publications with GAD1 and Slc32a1
 Gabrg2 shrna  >1 publications with GAD1 and Gabrg2
 Slc6a1 shrna  >1 publications with GAD1 and Slc6a1
 Abat shrna  >1 publications with GAD1 and Abat
 Calb2 shrna  >1 publications with GAD1 and Calb2
 Products by Pathway  Pathway Diagram
 Alanine And Aspartate Metabolism Pathway antibodies  Alanine And Aspartate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Biogenic Amine Synthesis Pathway antibodies  Biogenic Amine Synthesis Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 GABA (gamma-Aminobutyrate) Shunt Pathway antibodies  GABA (gamma-Aminobutyrate) Shunt Pathway Diagram
 GABA (gamma-Aminobutyrate) Shunt Pathway antibodies  GABA (gamma-Aminobutyrate) Shunt Pathway Diagram
 GABA Synthesis Pathway antibodies  GABA Synthesis Pathway Diagram
 GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies  GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
Diseases associated with GAD1 shrnaOrgans/Tissues associated with GAD1 shrna
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >76 publications with GAD1 and Mental Disorders
 Schizophrenia Antibodies  >52 publications with GAD1 and Schizophrenia
 Nervous System Diseases Antibodies  >33 publications with GAD1 and Nervous System Diseases
 Brain Diseases Antibodies  >28 publications with GAD1 and Brain Diseases
 Disease Models, Animal Antibodies  >23 publications with GAD1 and Disease Models, Animal
 Anxiety Disorders Antibodies  >9 publications with GAD1 and Anxiety Disorders
 Seizures Antibodies  >9 publications with GAD1 and Seizures
 Depressive Disorder Antibodies  >8 publications with GAD1 and Depressive Disorder
 Prenatal Exposure Delayed Effects Antibodies  >6 publications with GAD1 and Prenatal Exposure Delayed Effects
 Autistic Disorder Antibodies  >6 publications with GAD1 and Autistic Disorder
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >132 publications with GAD1 and Brain
 Spinal Cord Antibodies  >6 publications with GAD1 and Spinal Cord
 Eye Antibodies  >3 publications with GAD1 and Eye
 Pancreas Antibodies  >2 publications with GAD1 and Pancreas
 Embryonic Tissue Antibodies  >2 publications with GAD1 and Embryonic Tissue
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