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GINS2 shrna

Scan QR to view Datasheet Catalog #    MBS8259941 GINS2 shrna
Unit / Price
  DISCONTINUED
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GINS2, shRNA

 Also Known As   

GINS2 shRNA Plasmid (Human)

 Product Synonym Names    PSF2; DNA replication complex GINS protein PSF2; GINS complex subunit 2
 Product Gene Name   

GINS2 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF125098 mRNA
 3D Structure    ModBase 3D Structure for Q9Y248
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 Host    E Coli
 Species Reactivity    Human
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 Specificity    GINS2 shRNA Plasmid (Human) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down human GINS2 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of GINS2 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for GINS2 shrna

   shRNA Plasmid to inhibit GINS2 expression by RNA interference
 Applications Tested/Suitable for GINS2 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for GINS2. It may not necessarily be applicable to this product.
 NCBI GI #    7706367
 NCBI GeneID    51659
 NCBI Accession #    NP_057179.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016095.2 [Other Products]
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 UniProt Primary Accession #    Q9Y248 [Other Products]
 UniProt Secondary Accession #    Q6IAG9; D3DUM5 [Other Products]
 UniProt Related Accession #    Q9Y248 [Other Products]
 Molecular Weight    21,428 Da
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 NCBI Official Full Name    DNA replication complex GINS protein PSF2
 NCBI Official Synonym Full Names    GINS complex subunit 2
 NCBI Official Symbol    GINS2 [Similar Products]
 NCBI Official Synonym Symbols   
PSF2; Pfs2; HSPC037
[Similar Products]
 NCBI Protein Information    DNA replication complex GINS protein PSF2
 UniProt Protein Name    DNA replication complex GINS protein PSF2
 UniProt Synonym Protein Names   
GINS complex subunit 2
 Protein Family    DNA replication complex GINS protein
 UniProt Gene Name    GINS2 [Similar Products]
 UniProt Synonym Gene Names    PSF2 [Similar Products]
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 NCBI Summary for GINS2    The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
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 UniProt Comments for GINS2    The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
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 Research Articles on GINS2    1. GINS2 is overexpressed in cervical cancer.GINS2 is a novel indicator of pelvic lymph node metastasis in cervical cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GINS2 shrnaDiseases associated with GINS2 shrna
 Products by Pathway  Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 DNA Strand Elongation Pathway antibodies  DNA Strand Elongation Pathway Diagram
 S Phase Pathway antibodies  S Phase Pathway Diagram
 Synthesis Of DNA Pathway antibodies  Synthesis Of DNA Pathway Diagram
 Unwinding Of DNA Pathway antibodies  Unwinding Of DNA Pathway Diagram
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >2 publications with GINS2 and Skin Diseases
 Neoplasms Antibodies  >2 publications with GINS2 and Neoplasms
 Breast Neoplasms Antibodies  >2 publications with GINS2 and Breast Neoplasms
 Hematologic Diseases Antibodies  >1 publications with GINS2 and Hematologic Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with GINS2 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with GINS2 and Neoplasm Metastasis
 Bone Marrow Diseases Antibodies  >1 publications with GINS2 and Bone Marrow Diseases
Organs/Tissues associated with GINS2 shrna
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with GINS2 and Bone
 Blood Antibodies  >1 publications with GINS2 and Blood
 Bone Marrow Antibodies  >1 publications with GINS2 and Bone Marrow
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