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GJA3 shrna

Scan QR to view Datasheet Catalog #    MBS8286575 GJA3 shrna
Unit / Price
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

GJA3 shRNA Plasmid (Rat)

 Product Synonym Names    CXN-46; Gap junction alpha-3 protein; Connexin-46; Cx46
 Product Gene Name   

GJA3 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P29414
 Host    E Coli
 Species Reactivity    Rat
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 Specificity    GJA3 shRNA Plasmid (Rat) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down rat GJA3 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of GJA3 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for GJA3 shrna

   shRNA Plasmid to inhibit GJA3 expression by RNA interference
 Applications Tested/Suitable for GJA3 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for GJA3. It may not necessarily be applicable to this product.
 NCBI GI #    13242279
 NCBI GeneID    79217
 NCBI Accession #    NP_077352.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_024376.2 [Other Products]
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 UniProt Primary Accession #    P29414 [Other Products]
 UniProt Related Accession #    P29414 [Other Products]
 Molecular Weight    46,013 Da
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 NCBI Official Full Name    gap junction alpha-3 protein
 NCBI Official Synonym Full Names    gap junction protein, alpha 3
 NCBI Official Symbol    Gja3 [Similar Products]
 NCBI Protein Information    gap junction alpha-3 protein
 UniProt Protein Name    Gap junction alpha-3 protein
 UniProt Synonym Protein Names   
Connexin-46; Cx46
 Protein Family    Gap junction alpha-3 protein
 UniProt Gene Name    Gja3 [Similar Products]
 UniProt Synonym Gene Names    Cxn-46; Cx46 [Similar Products]
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 NCBI Summary for GJA3    lens gap junction protein; oligomerizes into intercellular channels and functions to exchange low molecular weight metabolites and ions between adjacent cells; induces voltage-gated currents in nonjunctional plasma membrane [RGD, Feb 2006]
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 UniProt Comments for GJA3    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
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 Research Articles on GJA3    1. the role of the charged residues at the end of TM-1 in voltage sensing in Cx26, Cx46, and Cx50.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GJA3 shrnaDiseases associated with GJA3 shrna
 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Disease Name  Pubmed Publications
 Hearing Loss Antibodies  >2 publications with GJA3 and Hearing Loss
 Abnormalities, Multiple Antibodies  >2 publications with GJA3 and Abnormalities, Multiple
 Skin Diseases Antibodies  >1 publications with GJA3 and Skin Diseases
Organs/Tissues associated with GJA3 shrna
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >2 publications with GJA3 and Heart
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