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KLHL2 shrna

Scan QR to view Datasheet Catalog #    MBS8257785 KLHL2 shrna
Unit / Price
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

KLHL2 shRNA Plasmid (Human)

 Product Synonym Names    Kelch-like protein 2; Actin-binding protein Mayven
 Product Gene Name   

KLHL2 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF059569 mRNA
 3D Structure    ModBase 3D Structure for O95198
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 Host    E Coli
 Species Reactivity    Human
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 Specificity    KLHL2 shRNA Plasmid (Human) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down human KLHL2 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of KLHL2 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for KLHL2 shrna

   shRNA Plasmid to inhibit KLHL2 expression by RNA interference
 Applications Tested/Suitable for KLHL2 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for KLHL2. It may not necessarily be applicable to this product.
 NCBI GI #    239835722
 NCBI GeneID    11275
 NCBI Accession #    NP_001154993.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001161521.1 [Other Products]
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 UniProt Primary Accession #    O95198 [Other Products]
 UniProt Secondary Accession #    Q8N484; Q8TBH5; A6NCM7; B2RD18; B4DFH7; F5H6M3 [Other Products]
 UniProt Related Accession #    O95198 [Other Products]
 Molecular Weight    56,086 Da
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 NCBI Official Full Name    kelch-like protein 2 isoform 2
 NCBI Official Synonym Full Names    kelch like family member 2
 NCBI Official Symbol    KLHL2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    kelch-like protein 2
 UniProt Protein Name    Kelch-like protein 2
 UniProt Synonym Protein Names   
Actin-binding protein Mayven
 Protein Family    Kelch-like protein
 UniProt Gene Name    KLHL2 [Similar Products]
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 UniProt Comments for KLHL2    Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
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 Research Articles on KLHL2    1. Co-expression of KLHL2 and Cullin3 decreases the abundance of WNK1, WNK3 and WNK4 within HEK293T cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KLHL2 shrnaDiseases associated with KLHL2 shrna
 Reference Product  PubMed Publications
 JUN shrna  >3 publications with KLHL2 and JUN
 CUL3 shrna  >3 publications with KLHL2 and CUL3
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >2 publications with KLHL2 and Hypertension
 Neoplasms, Experimental Antibodies  >1 publications with KLHL2 and Neoplasms, Experimental
Organs/Tissues associated with KLHL2 shrna
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with KLHL2 and Brain
 Blood Antibodies  >3 publications with KLHL2 and Blood
 Kidney Antibodies  >1 publications with KLHL2 and Kidney
 Vascular Antibodies  >1 publications with KLHL2 and Vascular
 Embryonic Tissue Antibodies  >1 publications with KLHL2 and Embryonic Tissue
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