Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow shRNA rightarrow MMP3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CRABP2 Antibody
 • ACSS1 Antibody
 • SLC25A6 Antibody
 • Protein Kinase C Delta (PKCD) ELISA Kit
 • Epidermal Basement Membrane Zone Antibody (EBMZ) ELISA Kit
 • Protein Interacting With Protein Kinase C, Alpha 1 (PICK1) ELISA Kit
 • Cyclin D (CD) ELISA Kit
 • Cytochrome B-561 (CYB561) ELISA Kit
 • Neonatal Thyroxine (NN-T4) ELISA Kit
 • Matrix Metalloproteinsae 1 (MMP-1) ELISA Kit
 • Osteoclase Differentiation Factor (ODF) ELISA Kit
 • Lectin-Galactose Binding-Soluble 3 (LGALS3) ELISA Kit
 • Adipose Differentiation Related Protein (ADRP) ELISA Kit
 • Ischemia Modified Albumin (IMA) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

MMP3 shrna

Scan QR to view Datasheet Catalog #    MBS8271592 MMP3 shrna
Unit / Price
0.15 mg  /  $540 +1 FREE 8GB USB
0.3 mg  /  $780 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MMP3, shRNA

 Also Known As   

MMP3 shRNA Plasmid (Mouse)

 Product Synonym Names    Stromelysin-1; SL-1; EMS-2; Matrix metalloproteinase-3; MMP-3; Transin-1
 Product Gene Name   

MMP3 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for P28862
 Host    E Coli
 Species Reactivity    Mouse
Section Bar
 Specificity    MMP3 shRNA Plasmid (Mouse) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
Section Bar
 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down mouse MMP3 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
Section Bar
 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of MMP3 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for MMP3 shrna

   shRNA Plasmid to inhibit MMP3 expression by RNA interference
 Applications Tested/Suitable for MMP3 shrna   

RNA interference (RNAi)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for MMP3. It may not necessarily be applicable to this product.
 NCBI GI #    6754714
 NCBI GeneID    17392
 NCBI Accession #    NP_034939.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_010809.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P28862 [Other Products]
 UniProt Related Accession #    P28862 [Other Products]
 Molecular Weight    53,845 Da
Table BarTOPTable Bar
 NCBI Official Full Name    stromelysin-1 preproprotein
 NCBI Official Synonym Full Names    matrix metallopeptidase 3
 NCBI Official Symbol    Mmp3 [Similar Products]
 NCBI Official Synonym Symbols   
SL-1; SLN1; Str1; EMS-2; MMP-3; SLN-1; STR-1; Stmy1
[Similar Products]
 NCBI Protein Information    stromelysin-1
 UniProt Protein Name    Stromelysin-1
 UniProt Synonym Protein Names   
EMS-2; Matrix metalloproteinase-3; MMP-3; Transin-1
 Protein Family    Stromelysin
 UniProt Gene Name    Mmp3 [Similar Products]
 UniProt Synonym Gene Names    SL-1; MMP-3 [Similar Products]
Section Bar
 NCBI Summary for MMP3    This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded protein is activated by the removal of an N-temrinal activation peptide to generate a zinc-dependent endopeptidase with a broad range of substrates such as proteoglycans, laminin, fibronectin, elastin, and collagens. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016]
Section Bar
 UniProt Comments for MMP3    Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Table BarTOPTable Bar
 Research Articles on MMP3    1. Overexpression of Mmp3 in 3T3-L1 preadipocytes inhibited differentiation. High fat diet-induced obesity downregulates adipocyte MMP3 expression to trigger adipogenesis, and adipocyte TIMP4 may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with MMP3 shrnaPathways associated with MMP3 shrna
 Reference Product  PubMed Publications
 Mmp9 shrna  >273 publications with MMP3 and Mmp9
 Mmp2 shrna  >209 publications with MMP3 and Mmp2
 Timp1 shrna  >113 publications with MMP3 and Timp1
 Timp2 shrna  >59 publications with MMP3 and Timp2
 Spp1 shrna  >11 publications with MMP3 and Spp1
 Ets1 shrna  >10 publications with MMP3 and Ets1
 Dcn shrna  >5 publications with MMP3 and Dcn
 Cdh1 shrna  >5 publications with MMP3 and Cdh1
 Col18a1 shrna  >2 publications with MMP3 and Col18a1
 Mapk8 shrna  >1 publications with MMP3 and Mapk8
 Products by Pathway  Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 EGFR Transactivation By Gastrin Pathway antibodies  EGFR Transactivation By Gastrin Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Matrix Metalloproteinases Pathway antibodies  Matrix Metalloproteinases Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 TNF Signaling Pathway antibodies  TNF Signaling Pathway Diagram
Diseases associated with MMP3 shrnaOrgans/Tissues associated with MMP3 shrna
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >264 publications with MMP3 and Inflammation
 Necrosis Antibodies  >146 publications with MMP3 and Necrosis
 Disease Models, Animal Antibodies  >120 publications with MMP3 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >120 publications with MMP3 and Cardiovascular Diseases
 Neoplasm Invasiveness Antibodies  >61 publications with MMP3 and Neoplasm Invasiveness
 Heart Diseases Antibodies  >52 publications with MMP3 and Heart Diseases
 Fibrosis Antibodies  >52 publications with MMP3 and Fibrosis
 Arthritis, Experimental Antibodies  >48 publications with MMP3 and Arthritis, Experimental
 Pain Antibodies  >48 publications with MMP3 and Pain
 Atherosclerosis Antibodies  >44 publications with MMP3 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Joint Antibodies  >266 publications with MMP3 and Joint
 Bone Antibodies  >173 publications with MMP3 and Bone
 Connective Tissue Antibodies  >115 publications with MMP3 and Connective Tissue
 Lung Antibodies  >70 publications with MMP3 and Lung
 Intestine Antibodies  >14 publications with MMP3 and Intestine
 Mammary Gland Antibodies  >10 publications with MMP3 and Mammary Gland
 Pancreas Antibodies  >3 publications with MMP3 and Pancreas
 Oviduct Antibodies  >2 publications with MMP3 and Oviduct
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions