NP_001287862.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,612 Da
NCBI Official Full Name
neuropeptide S receptor B short
NCBI Official Synonym Full Names
neuropeptide S receptor 1
NCBI Official Synonym Symbols
GPRA; NPSR; VRR1; ASRT2; PGR14; GPR154 [Similar Products]
NCBI Protein Information
neuropeptide S receptor
UniProt Protein Name
Neuropeptide S receptor
UniProt Synonym Protein Names
G-protein coupled receptor 154; G-protein coupled receptor PGR14; G-protein coupled receptor for asthma susceptibility
UniProt Synonym Gene Names
NCBI Summary for NPSR1
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Comments for NPSR1
G-protein coupled receptor for neuropeptide S (NPS) (PubMed:16790440). Promotes mobilization of intracellular Ca2+ stores (PubMed:16790440). Inhibits cell growth in response to NPS binding (PubMed:15947423). Involved in pathogenesis of asthma and other IgE-mediated diseases.
Research Articles on NPSR1
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Pathways associated with NPSR1 shrna
Diseases associated with NPSR1 shrna
Organs/Tissues associated with NPSR1 shrna
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