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SHC4 shrna

Scan QR to view Datasheet Catalog #    MBS8283191 SHC4 shrna
Unit / Price
0.15 mg  /  $540 +1 FREE 8GB USB
0.3 mg  /  $780 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SHC4, shRNA

 Also Known As   

SHC4 shRNA Plasmid (Mouse)

 Product Synonym Names    SHCD; SHC-transforming protein 4; Rai-like protein; RaLP; SHC-transforming protein D; mShcD; Src homology 2 domain-containing-transforming protein C4; SH2 domain protein C4
 Product Gene Name   

SHC4 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q6S5L9
 Host    E Coli
 Species Reactivity    Mouse
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 Specificity    SHC4 shRNA Plasmid (Mouse) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down mouse SHC4 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of SHC4 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for SHC4 shrna

   shRNA Plasmid to inhibit SHC4 expression by RNA interference
 Applications Tested/Suitable for SHC4 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for SHC4. It may not necessarily be applicable to this product.
 NCBI GI #    39841043
 NCBI GeneID    271849
 NCBI Accession #    NP_950187.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_199022.2 [Other Products]
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 UniProt Primary Accession #    Q6S5L9 [Other Products]
 UniProt Related Accession #    Q6S5L9 [Other Products]
 Molecular Weight    68,519 Da
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 NCBI Official Full Name    SHC-transforming protein 4
 NCBI Official Synonym Full Names    SHC (Src homology 2 domain containing) family, member 4
 NCBI Official Symbol    Shc4 [Similar Products]
 NCBI Official Synonym Symbols   
RaLP; Gm685; 6230417E10Rik; 9930029B02Rik
[Similar Products]
 NCBI Protein Information    SHC-transforming protein 4
 UniProt Protein Name    SHC-transforming protein 4
 UniProt Synonym Protein Names   
Rai-like protein; RaLP; SHC-transforming protein D; mShcD; Src homology 2 domain-containing-transforming protein C4; SH2 domain protein C4
 Protein Family    SHC-transforming protein
 UniProt Gene Name    Shc4 [Similar Products]
 UniProt Synonym Gene Names    Shcd; RaLP; mShcD; SH2 domain protein C4 [Similar Products]
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 UniProt Comments for SHC4    Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
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 Research Articles on SHC4    1. Shc4 is an important modulator in the switch of key pathway(s) involved in determining epiblast stem cell identity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with SHC4 shrnaDiseases associated with SHC4 shrna
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with SHC4 and Neoplasms
Organs/Tissues associated with SHC4 shrna
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with SHC4 and Brain
 Uncharacterized Tissue Antibodies  >1 publications with SHC4 and Uncharacterized Tissue
 Embryonic Tissue Antibodies  >1 publications with SHC4 and Embryonic Tissue
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