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TEAD1 shrna

Scan QR to view Datasheet Catalog #    MBS8254835 TEAD1 shrna
Unit / Price
0.15 mg  /  $540 +1 FREE 8GB USB
0.3 mg  /  $780 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TEAD1, shRNA

 Also Known As   

TEAD1 shRNA Plasmid (Human)

 Product Synonym Names    TCF13; TEF1; Transcriptional enhancer factor TEF-1; NTEF-1; Protein GT-IIC; TEA domain family member 1; TEAD-1; Transcription factor 13; TCF-13
 Product Gene Name   

TEAD1 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M63896 Genomic DNA
 3D Structure    ModBase 3D Structure for P28347
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 Host    E Coli
 Species Reactivity    Human
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 Specificity    TEAD1 shRNA Plasmid (Human) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down human TEAD1 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of TEAD1 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for TEAD1 shrna

   shRNA Plasmid to inhibit TEAD1 expression by RNA interference
 Applications Tested/Suitable for TEAD1 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for TEAD1. It may not necessarily be applicable to this product.
 NCBI GI #    296434319
 NCBI GeneID    7003
 NCBI Accession #    NP_068780.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021961.5 [Other Products]
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 UniProt Primary Accession #    P28347 [Other Products]
 UniProt Secondary Accession #    A4FUP2; E7EV65 [Other Products]
 UniProt Related Accession #    P28347 [Other Products]
 Molecular Weight    40,000 Da
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 NCBI Official Full Name    transcriptional enhancer factor TEF-1
 NCBI Official Synonym Full Names    TEA domain transcription factor 1
 NCBI Official Symbol    TEAD1 [Similar Products]
 NCBI Official Synonym Symbols   
AA; REF1; TCF13; TEF-1; NTEF-1; TCF-13; TEAD-1
[Similar Products]
 NCBI Protein Information    transcriptional enhancer factor TEF-1
 UniProt Protein Name    Transcriptional enhancer factor TEF-1
 UniProt Synonym Protein Names   
NTEF-1; Protein GT-IIC; TEA domain family member 1; TEAD-1; Transcription factor 13; TCF-13
 Protein Family    Transcriptional enhancer factor
 UniProt Gene Name    TEAD1 [Similar Products]
 UniProt Synonym Gene Names    TCF13; TEF1; TEAD-1; TCF-13 [Similar Products]
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 NCBI Summary for TEAD1    This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]
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 UniProt Comments for TEAD1    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
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 Research Articles on TEAD1    1. MYC and TEAD activity is able to stratify different breast cancer subtypes in large panels of breast cancer patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TEAD1 shrnaPathways associated with TEAD1 shrna
 Reference Product  PubMed Publications
 YAP1 shrna  >8 publications with TEAD1 and YAP1
 SRF shrna  >7 publications with TEAD1 and SRF
 VGLL2 shrna  >4 publications with TEAD1 and VGLL2
 TBP shrna  >4 publications with TEAD1 and TBP
 MAX shrna  >4 publications with TEAD1 and MAX
 VGLL4 shrna  >2 publications with TEAD1 and VGLL4
 MEF2C shrna  >2 publications with TEAD1 and MEF2C
 VGLL1 shrna  >1 publications with TEAD1 and VGLL1
 Products by Pathway  Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway antibodies  YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway Diagram
Diseases associated with TEAD1 shrnaOrgans/Tissues associated with TEAD1 shrna
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >20 publications with TEAD1 and Neoplasms
 Hypertrophy Antibodies  >8 publications with TEAD1 and Hypertrophy
 Congenital Abnormalities Antibodies  >4 publications with TEAD1 and Congenital Abnormalities
 Cardiomegaly Antibodies  >3 publications with TEAD1 and Cardiomegaly
 Atrophy Antibodies  >3 publications with TEAD1 and Atrophy
 Breast Neoplasms Antibodies  >2 publications with TEAD1 and Breast Neoplasms
 Nervous System Diseases Antibodies  >2 publications with TEAD1 and Nervous System Diseases
 Abnormalities, Multiple Antibodies  >1 publications with TEAD1 and Abnormalities, Multiple
 Skin Diseases Antibodies  >1 publications with TEAD1 and Skin Diseases
 Kidney Diseases Antibodies  >1 publications with TEAD1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >67 publications with TEAD1 and Muscle
 Heart Antibodies  >32 publications with TEAD1 and Heart
 Embryonic Tissue Antibodies  >30 publications with TEAD1 and Embryonic Tissue
 Placenta Antibodies  >11 publications with TEAD1 and Placenta
 Brain Antibodies  >7 publications with TEAD1 and Brain
 Vascular Antibodies  >7 publications with TEAD1 and Vascular
 Kidney Antibodies  >6 publications with TEAD1 and Kidney
 Lung Antibodies  >6 publications with TEAD1 and Lung
 Eye Antibodies  >5 publications with TEAD1 and Eye
 Bone Antibodies  >5 publications with TEAD1 and Bone
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