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TRIM33 shrna

Scan QR to view Datasheet Catalog #    MBS8279329 TRIM33 shrna
Unit / Price
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

TRIM33 shRNA Plasmid (Mouse)

 Product Synonym Names    KIAA1113; E3 ubiquitin-protein ligase TRIM33; Ectodermin homolog; Transcription intermediary factor 1-gamma; TIF1-gamma; Tripartite motif-containing protein 33
 Product Gene Name   

TRIM33 shrna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q99PP7
 Host    E Coli
 Species Reactivity    Mouse
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 Specificity    TRIM33 shRNA Plasmid (Mouse) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
 Form/Format    Lyophilized Powder
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 Quality Control    The sequence of shRNA is guaranteed by sequencing.
 Directions for Use    Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
 Components    We offer 3 different plasmids which knock down mouse TRIM33 gene specifically. Each vial contains 50 ug of lyophilized shRNA.
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 Preparation and Storage    Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
 Other Notes    Small volumes of TRIM33 shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TRIM33 shrna

   shRNA Plasmid to inhibit TRIM33 expression by RNA interference
 Applications Tested/Suitable for TRIM33 shrna   

RNA interference (RNAi)

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NCBI/Uniprot data below describe general gene information for TRIM33. It may not necessarily be applicable to this product.
 NCBI GI #    119637830
 NCBI GeneID    94093
 NCBI Accession #    NP_001073299.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001079830.2 [Other Products]
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 UniProt Primary Accession #    Q99PP7 [Other Products]
 UniProt Secondary Accession #    Q6SI71; Q6ZPX5 [Other Products]
 UniProt Related Accession #    Q99PP7 [Other Products]
 Molecular Weight    121,850 Da
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 NCBI Official Full Name    E3 ubiquitin-protein ligase TRIM33 isoform 2
 NCBI Official Synonym Full Names    tripartite motif-containing 33
 NCBI Official Symbol    Trim33 [Similar Products]
 NCBI Official Synonym Symbols   
Ecto; Tif1g; AI413936; 8030451N04Rik
[Similar Products]
 NCBI Protein Information    E3 ubiquitin-protein ligase TRIM33
 UniProt Protein Name    E3 ubiquitin-protein ligase TRIM33
 UniProt Synonym Protein Names   
Ectodermin homolog; RING-type E3 ubiquitin transferase TRIM33Curated; Transcription intermediary factor 1-gamma; TIF1-gamma; Tripartite motif-containing protein 33
 Protein Family    E3 ubiquitin-protein ligase
 UniProt Gene Name    Trim33 [Similar Products]
 UniProt Synonym Gene Names    Kiaa1113; TIF1-gamma [Similar Products]
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 UniProt Comments for TRIM33    Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway (). May act as a transcriptional repressor (). Inhibits the transcriptional response to TGF-beta/BMP signaling cascade (). Plays a role in the control of cell proliferation (). Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade) ().
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 Research Articles on TRIM33    1. these results indicate that Trim33 deficiency leads to the expansion of a subset of myeloid cells characterizing the myelodysplastic/myeloproliferative neoplasm.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TRIM33 shrnaDiseases associated with TRIM33 shrna
 Products by Pathway  Pathway Diagram
 PluriNetWork Pathway antibodies  PluriNetWork Pathway Diagram
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >4 publications with TRIM33 and Adenocarcinoma
 Translocation, Genetic Antibodies  >2 publications with TRIM33 and Translocation, Genetic
 Carcinoma, Hepatocellular Antibodies  >2 publications with TRIM33 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with TRIM33 and Liver Diseases
 Skin Diseases Antibodies  >1 publications with TRIM33 and Skin Diseases
 Kidney Neoplasms Antibodies  >1 publications with TRIM33 and Kidney Neoplasms
 Disease Models, Animal Antibodies  >1 publications with TRIM33 and Disease Models, Animal
Organs/Tissues associated with TRIM33 shrna
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with TRIM33 and Blood
 Liver Antibodies  >3 publications with TRIM33 and Liver
 Bone Marrow Antibodies  >3 publications with TRIM33 and Bone Marrow
 Embryonic Tissue Antibodies  >3 publications with TRIM33 and Embryonic Tissue
 Pancreas Antibodies  >2 publications with TRIM33 and Pancreas
 Spinal Cord Antibodies  >1 publications with TRIM33 and Spinal Cord
 Lung Antibodies  >1 publications with TRIM33 and Lung
 Testis Antibodies  >1 publications with TRIM33 and Testis
 Thymus Antibodies  >1 publications with TRIM33 and Thymus
 Brain Antibodies  >1 publications with TRIM33 and Brain
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