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ABCA13 sirna

Scan QR to view Datasheet Catalog #    MBS8203836 ABCA13 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

ABCA13 siRNA (Mouse)

 Product Synonym Names    ATP-binding cassette sub-family A member 13
 Product Gene Name   

ABCA13 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q5SSE9
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    ABCA13 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse ABCA13 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of ABCA13 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for ABCA13 sirna

   siRNA to inhibit ABCA13 expression using RNA interference
 Applications Tested/Suitable for ABCA13 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for ABCA13. It may not necessarily be applicable to this product.
 NCBI GI #    116292744
 NCBI GeneID    268379
 NCBI Accession #    NP_839990.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_178259.3 [Other Products]
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 UniProt Primary Accession #    Q5SSE9 [Other Products]
 UniProt Secondary Accession #    Q80T20; Q8BHZ2; Q8CB91 [Other Products]
 UniProt Related Accession #    Q5SSE9 [Other Products]
 Molecular Weight    12,753 Da
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 NCBI Official Full Name    ATP-binding cassette sub-family A member 13
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family A (ABC1), member 13
 NCBI Official Symbol    Abca13 [Similar Products]
 NCBI Official Synonym Symbols   
AI956815; 9830132L24; A930002G16Rik
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family A member 13
 UniProt Protein Name    ATP-binding cassette sub-family A member 13
 Protein Family    ATP-binding cassette sub-family
 UniProt Gene Name    Abca13 [Similar Products]
 UniProt Entry Name    ABCAD_MOUSE
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 UniProt Comments for ABCA13    ABCA13: In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: intracellular membrane-bound organelle; membrane; integral to plasma membrane; integral to membrane

Molecular Function: phospholipid transporter activity; ATPase activity, coupled to transmembrane movement of substances; transporter activity; cholesterol transporter activity; ATPase activity; nucleotide binding; ATP binding

Biological Process: phospholipid efflux; transport; cholesterol efflux; transmembrane transport
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 Research Articles on ABCA13    1. T4031A replacement affects the function of ABCA13 in the brain
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCA13 sirnaDiseases associated with ABCA13 sirna
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with ABCA13 and Kidney Diseases
 Male Urogenital Diseases Antibodies  >1 publications with ABCA13 and Male Urogenital Diseases
 Inflammation Antibodies  >1 publications with ABCA13 and Inflammation
 Disease Progression Antibodies  >1 publications with ABCA13 and Disease Progression
 Colorectal Neoplasms Antibodies  >1 publications with ABCA13 and Colorectal Neoplasms
Organs/Tissues associated with ABCA13 sirna
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >2 publications with ABCA13 and Bone Marrow
 Bone Antibodies  >2 publications with ABCA13 and Bone
 Kidney Antibodies  >2 publications with ABCA13 and Kidney
 Embryonic Tissue Antibodies  >1 publications with ABCA13 and Embryonic Tissue
 Liver Antibodies  >1 publications with ABCA13 and Liver
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