NP_001013203.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
72,226 Da
NCBI Official Full Name
atypical kinase ADCK3, mitochondrial
NCBI Official Synonym Full Names
aarF domain containing kinase 3
NCBI Official Synonym Symbols
NCBI Protein Information
atypical kinase ADCK3, mitochondrial
UniProt Protein Name
Atypical kinase ADCK3, mitochondrial
UniProt Synonym Protein Names
Chaperone activity of bc1 complex-like
UniProt Synonym Gene Names
UniProt Entry Name
ADCK3_RAT
UniProt Comments for ADCK3
ADCK3: May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain. Defects in ADCK3 are the cause of coenzyme Q10 deficiency, primary, type 4 (COQ10D4). An autosomal recessive disorder characterized by childhood-onset of cerebellar ataxia and exercise intolerance. Patient manifest gait ataxia and cerebellar atrophy with slow progression. Additional features include brisk tendon reflexes and Hoffmann sign, variable psychomotor retardation and variable seizures. Belongs to the protein kinase superfamily. ADCK protein kinase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, other; Transferase; Protein kinase, Ser/Thr (non-receptor); Mitochondrial; Kinase, protein; EC 2.7.11.-; Protein kinase, atypical; ATYPICAL group; ABC1 family; ABC1-A subfamily
Cellular Component: mitochondrion
Molecular Function: protein serine/threonine kinase activity; ATP binding
Biological Process: ubiquinone biosynthetic process; protein amino acid phosphorylation
Research Articles on ADCK3
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Products associated with ADCK3 sirna
Diseases associated with ADCK3 sirna
Organs/Tissues associated with ADCK3 sirna
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