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C1orf61 sirna

Scan QR to view Datasheet Catalog #    MBS8233301 C1orf61 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C1orf61, siRNA

 Also Known As   

C1orf61 siRNA (Human)

 Product Synonym Names    CROC4; Protein CROC-4; Contingent replication of cDNA 4
 Product Gene Name   

C1orf61 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q13536
 Host    Synthetic
 Species Reactivity    Human
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 Specificity    C1orf61 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human C1orf61 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of C1orf61 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for C1orf61 sirna

   siRNA to inhibit C1orf61 expression using RNA interference
 Applications Tested/Suitable for C1orf61 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for C1orf61. It may not necessarily be applicable to this product.
 NCBI GI #    5453625
 NCBI GeneID    10485
 NCBI Accession #    NP_006356.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006365.1 [Other Products]
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 UniProt Primary Accession #    Q13536 [Other Products]
 UniProt Secondary Accession #    B1ALL5; B1ALL8 [Other Products]
 UniProt Related Accession #    Q13536 [Other Products]
 Molecular Weight    17,231 Da
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 NCBI Official Full Name    protein CROC-4
 NCBI Official Synonym Full Names    chromosome 1 open reading frame 61
 NCBI Official Symbol    C1orf61 [Similar Products]
 NCBI Official Synonym Symbols   
CROC4
[Similar Products]
 NCBI Protein Information    protein CROC-4
 UniProt Protein Name    Protein CROC-4
 UniProt Synonym Protein Names   
Contingent replication of cDNA 4
 Protein Family    Protein
 UniProt Gene Name    C1orf61 [Similar Products]
 UniProt Synonym Gene Names    CROC4 [Similar Products]
 UniProt Entry Name    CROC4_HUMAN
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 UniProt Comments for C1orf61    CROC4: May play a role in FOS signaling pathways involved in development and remodeling of neurons. Promotes transcription of the FOS promoter.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: nucleus
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with C1orf61 sirnaDiseases associated with C1orf61 sirna
 Reference Product  PubMed Publications
 CDK5 sirna  >1 publications with C1orf61 and CDK5
 Disease Name  Pubmed Publications
 Bone Diseases, Metabolic Antibodies  >1 publications with C1orf61 and Bone Diseases, Metabolic
 Cell Transformation, Neoplastic Antibodies  >1 publications with C1orf61 and Cell Transformation, Neoplastic
Organs/Tissues associated with C1orf61 sirna
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with C1orf61 and Brain
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