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CALB2 sirna

Scan QR to view Datasheet Catalog #    MBS8205026 CALB2 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CALB2, siRNA

 Also Known As   

CALB2 siRNA (Mouse)

 Product Synonym Names    Calretinin; CR
 Product Gene Name   

CALB2 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q08331
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    CALB2 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse CALB2 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of CALB2 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for CALB2 sirna

   siRNA to inhibit CALB2 expression using RNA interference
 Applications Tested/Suitable for CALB2 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for CALB2. It may not necessarily be applicable to this product.
 NCBI GI #    34098931
 NCBI GeneID    12308
 NCBI Accession #    NP_031612.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007586.1 [Other Products]
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 UniProt Primary Accession #    Q08331 [Other Products]
 UniProt Secondary Accession #    Q60964; Q9JM81 [Other Products]
 UniProt Related Accession #    Q08331 [Other Products]
 Molecular Weight    31,373 Da
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 NCBI Official Full Name    calretinin
 NCBI Official Synonym Full Names    calbindin 2
 NCBI Official Symbol    Calb2 [Similar Products]
 NCBI Official Synonym Symbols   
CR
[Similar Products]
 NCBI Protein Information    calretinin
 UniProt Protein Name    Calretinin
 Protein Family    Calretinin
 UniProt Gene Name    Calb2 [Similar Products]
 UniProt Synonym Gene Names    CR [Similar Products]
 UniProt Entry Name    CALB2_MOUSE
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 UniProt Comments for CALB2    CALB2: Calretinin is a calcium-binding protein which is abundant in auditory neurons. Belongs to the calbindin family.

Protein type: Calcium-binding

Cellular Component: cytoplasm; gap junction; terminal button; cytosol; nucleus

Molecular Function: metal ion binding; calcium ion binding

Biological Process: cytosolic calcium ion homeostasis
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 Research Articles on CALB2    1. Melatonin favors calretinin-positive neurons in the dentate gyrus of young mice but hippocampal neurogenesis and plasma levels of melatonin decrease during aging.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CALB2 sirnaPathways associated with CALB2 sirna
 Reference Product  PubMed Publications
 Bdnf sirna  >13 publications with CALB2 and Bdnf
 Pax6 sirna  >8 publications with CALB2 and Pax6
 Tubb3 sirna  >5 publications with CALB2 and Tubb3
 Rbfox3 sirna  >3 publications with CALB2 and Rbfox3
 Dlx1 sirna  >3 publications with CALB2 and Dlx1
 Pvalb sirna  >1 publications with CALB2 and Pvalb
 Htt sirna  >1 publications with CALB2 and Htt
 Cacna1a sirna  >1 publications with CALB2 and Cacna1a
 Gad1 sirna  >1 publications with CALB2 and Gad1
 Products by Pathway  Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram
Diseases associated with CALB2 sirnaOrgans/Tissues associated with CALB2 sirna
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >140 publications with CALB2 and Nervous System Diseases
 Brain Diseases Antibodies  >111 publications with CALB2 and Brain Diseases
 Ovarian Neoplasms Antibodies  >57 publications with CALB2 and Ovarian Neoplasms
 Nerve Degeneration Antibodies  >51 publications with CALB2 and Nerve Degeneration
 Disease Models, Animal Antibodies  >46 publications with CALB2 and Disease Models, Animal
 Mental Disorders Antibodies  >45 publications with CALB2 and Mental Disorders
 Seizures Antibodies  >29 publications with CALB2 and Seizures
 Movement Disorders Antibodies  >24 publications with CALB2 and Movement Disorders
 Pain Antibodies  >19 publications with CALB2 and Pain
 Hyperplasia Antibodies  >18 publications with CALB2 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >701 publications with CALB2 and Brain
 Eye Antibodies  >81 publications with CALB2 and Eye
 Embryonic Tissue Antibodies  >59 publications with CALB2 and Embryonic Tissue
 Intestine Antibodies  >50 publications with CALB2 and Intestine
 Spinal Cord Antibodies  >31 publications with CALB2 and Spinal Cord
 Olfactory Mucosa Antibodies  >10 publications with CALB2 and Olfactory Mucosa
 Oviduct Antibodies  >6 publications with CALB2 and Oviduct
 Pituitary Gland Antibodies  >4 publications with CALB2 and Pituitary Gland
 Thymus Antibodies  >4 publications with CALB2 and Thymus
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