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CSMD3 sirna

Scan QR to view Datasheet Catalog #    MBS8222326 CSMD3 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CSMD3, siRNA

 Also Known As   

CSMD3 siRNA (Human)

 Product Synonym Names    KIAA1894; CUB and sushi domain-containing protein 3; CUB and sushi multiple domains protein 3
 Product Gene Name   

CSMD3 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608399
 3D Structure    ModBase 3D Structure for Q7Z407
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 Host    Synthetic
 Species Reactivity    Human
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 Specificity    CSMD3 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human CSMD3 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of CSMD3 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CSMD3 sirna

   siRNA to inhibit CSMD3 expression using RNA interference
 Applications Tested/Suitable for CSMD3 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for CSMD3. It may not necessarily be applicable to this product.
 NCBI GI #    205277354
 NCBI GeneID    114788
 NCBI Accession #    NP_443132.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_052900.2 [Other Products]
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 UniProt Primary Accession #    Q7Z407 [Other Products]
 UniProt Secondary Accession #    Q96PZ3 [Other Products]
 UniProt Related Accession #    Q7Z407 [Other Products]
 Molecular Weight    294,834 Da
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 NCBI Official Full Name    CUB and sushi domain-containing protein 3 isoform 3
 NCBI Official Synonym Full Names    CUB and Sushi multiple domains 3
 NCBI Official Symbol    CSMD3 [Similar Products]
 NCBI Protein Information    CUB and sushi domain-containing protein 3
 UniProt Protein Name    CUB and sushi domain-containing protein 3
 UniProt Synonym Protein Names   
CUB and sushi multiple domains protein 3
 Protein Family    CUB and sushi domain-containing protein
 UniProt Gene Name    CSMD3 [Similar Products]
 UniProt Synonym Gene Names    KIAA1894 [Similar Products]
 UniProt Entry Name    CSMD3_HUMAN
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 UniProt Comments for CSMD3    CSMD3: Belongs to the CSMD family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q23.3

Cellular Component: integral to membrane; plasma membrane
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 Research Articles on CSMD3    1. Nonsynonymous variants of CSMD3 is associated with familial colorectal cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CSMD3 sirnaDiseases associated with CSMD3 sirna
 Reference Product  PubMed Publications
 CNTNAP2 sirna  >1 publications with CSMD3 and CNTNAP2
 EXT1 sirna  >1 publications with CSMD3 and EXT1
 TRPS1 sirna  >1 publications with CSMD3 and TRPS1
 ANXA13 sirna  >1 publications with CSMD3 and ANXA13
 Disease Name  Pubmed Publications
 Chromosome Aberrations Antibodies  >3 publications with CSMD3 and Chromosome Aberrations
 Carcinoma, Squamous Cell Antibodies  >2 publications with CSMD3 and Carcinoma, Squamous Cell
 Vascular Diseases Antibodies  >1 publications with CSMD3 and Vascular Diseases
 Lung Neoplasms Antibodies  >1 publications with CSMD3 and Lung Neoplasms
 Immune System Diseases Antibodies  >1 publications with CSMD3 and Immune System Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with CSMD3 and Neurobehavioral Manifestations
 Male Urogenital Diseases Antibodies  >1 publications with CSMD3 and Male Urogenital Diseases
 Learning Disorders Antibodies  >1 publications with CSMD3 and Learning Disorders
 Autistic Disorder Antibodies  >1 publications with CSMD3 and Autistic Disorder
Organs/Tissues associated with CSMD3 sirna
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with CSMD3 and Brain
 Eye Antibodies  >1 publications with CSMD3 and Eye
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