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DAP3 sirna

Scan QR to view Datasheet Catalog #    MBS8211033 DAP3 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   

DAP3 siRNA (Mouse)

 Product Synonym Names    MRPS29; 28S ribosomal protein S29 mitochondrial; MRP-S29; S29mt; Death-associated protein 3; DAP-3
 Product Gene Name   

DAP3 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9ER88
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    DAP3 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse DAP3 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of DAP3 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for DAP3 sirna

   siRNA to inhibit DAP3 expression using RNA interference
 Applications Tested/Suitable for DAP3 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for DAP3. It may not necessarily be applicable to this product.
 NCBI GI #    256985205
 NCBI GeneID    65111
 NCBI Accession #    NP_001158005.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001164533.1 [Other Products]
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 UniProt Primary Accession #    Q9ER88 [Other Products]
 UniProt Secondary Accession #    Q8C2B2; Q8CCQ8; Q8VCK8; Q9CRT4; Q9CS11; Q9D5V9 [Other Products]
 UniProt Related Accession #    Q9ER88 [Other Products]
 Molecular Weight    41,536 Da
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 NCBI Official Full Name    28S ribosomal protein S29, mitochondrial isoform 1
 NCBI Official Synonym Full Names    death associated protein 3
 NCBI Official Symbol    Dap3 [Similar Products]
 NCBI Official Synonym Symbols   
DAP-3; S29mt; MRP-S29; 4921514D13Rik
[Similar Products]
 NCBI Protein Information    28S ribosomal protein S29, mitochondrial
 UniProt Protein Name    28S ribosomal protein S29, mitochondrial
 UniProt Synonym Protein Names   
Death-associated protein 3; DAP-3
 Protein Family    28S ribosomal protein
 UniProt Gene Name    Dap3 [Similar Products]
 UniProt Synonym Gene Names    Mrps29; MRP-S29; S29mt; DAP-3 [Similar Products]
 UniProt Entry Name    RT29_MOUSE
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 UniProt Comments for DAP3    DAP3: Involved in mediating interferon-gamma-induced cell death. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Mitochondrial; Apoptosis

Cellular Component: nucleoplasm; small ribosomal subunit; mitochondrion; mitochondrial matrix; mitochondrial ribosome; nucleolus; ribosome; ribonucleoprotein complex; nucleus

Biological Process: apoptotic mitochondrial changes; apoptosis
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 Research Articles on DAP3    1. DAP3 is critical for TCR-mediated induction of apoptosis at the downstream of Nur77.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DAP3 sirnaDiseases associated with DAP3 sirna
 Products by Pathway  Pathway Diagram
 Mitochondrial Translation Pathway antibodies  Mitochondrial Translation Pathway Diagram
 Mitochondrial Translation Elongation Pathway antibodies  Mitochondrial Translation Elongation Pathway Diagram
 Mitochondrial Translation Initiation Pathway antibodies  Mitochondrial Translation Initiation Pathway Diagram
 Mitochondrial Translation Termination Pathway antibodies  Mitochondrial Translation Termination Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >9 publications with DAP3 and Necrosis
 Immune System Diseases Antibodies  >7 publications with DAP3 and Immune System Diseases
 Embryo Loss Antibodies  >1 publications with DAP3 and Embryo Loss
 Cardiovascular Diseases Antibodies  >1 publications with DAP3 and Cardiovascular Diseases
 Atrophy Antibodies  >1 publications with DAP3 and Atrophy
 Nervous System Diseases Antibodies  >1 publications with DAP3 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with DAP3 and Disease Models, Animal
 Learning Disorders Antibodies  >1 publications with DAP3 and Learning Disorders
 Inflammation Antibodies  >1 publications with DAP3 and Inflammation
 Breast Neoplasms Antibodies  >1 publications with DAP3 and Breast Neoplasms
Organs/Tissues associated with DAP3 sirna
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with DAP3 and Blood
 Thymus Antibodies  >2 publications with DAP3 and Thymus
 Pancreas Antibodies  >1 publications with DAP3 and Pancreas
 Bone Antibodies  >1 publications with DAP3 and Bone
 Lymph Node Antibodies  >1 publications with DAP3 and Lymph Node
 Stomach Antibodies  >1 publications with DAP3 and Stomach
 Heart Antibodies  >1 publications with DAP3 and Heart
 Ovary Antibodies  >1 publications with DAP3 and Ovary
 Liver Antibodies  >1 publications with DAP3 and Liver
 Adipose Tissue Antibodies  >1 publications with DAP3 and Adipose Tissue
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