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HEBP1 sirna

Scan QR to view Datasheet Catalog #    MBS8204794 HEBP1 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HEBP1, siRNA

★Popular Item★
 Also Known As   

HEBP1 siRNA (Mouse)

 Product Synonym Names    HBP; Heme-binding protein 1; p22HBP
 Product Gene Name   

HEBP1 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9R257
 Host    Synthetic
 Species Reactivity    Mouse
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 Specificity    HEBP1 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse HEBP1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of HEBP1 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for HEBP1 sirna

   siRNA to inhibit HEBP1 expression using RNA interference
 Applications Tested/Suitable for HEBP1 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for HEBP1. It may not necessarily be applicable to this product.
 NCBI GI #    124001580
 NCBI GeneID    15199
 NCBI Accession #    NP_038574.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_013546.2 [Other Products]
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 UniProt Primary Accession #    Q9R257 [Other Products]
 UniProt Secondary Accession #    O88814 [Other Products]
 UniProt Related Accession #    Q9R257 [Other Products]
 Molecular Weight    21,067 Da
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 NCBI Official Full Name    heme-binding protein 1
 NCBI Official Synonym Full Names    heme binding protein 1
 NCBI Official Symbol    Hebp1 [Similar Products]
 NCBI Official Synonym Symbols   
Hebp
[Similar Products]
 NCBI Protein Information    heme-binding protein 1
 UniProt Protein Name    Heme-binding protein 1
 UniProt Synonym Protein Names   
p22HBP
 Protein Family    Heme-binding protein
 UniProt Gene Name    Hebp1 [Similar Products]
 UniProt Synonym Gene Names    Hbp [Similar Products]
 UniProt Entry Name    HEBP1_MOUSE
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 UniProt Comments for HEBP1    HEBP1: May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N- methylprotoporphyrin with similar affinities. Belongs to the HEBP family.

Cellular Component: mitochondrion; cytoplasm; cytosol

Molecular Function: heme binding

Biological Process: heme metabolic process
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 Research Articles on HEBP1    1. Results present a systematic molecular modeling study of the binding properties of murine and human p22HBP protein (heme-binding protein) with four tetrapyrrole ring systems belonging to the heme biosynthetic pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HEBP1 sirnaPathways associated with HEBP1 sirna
 Reference Product  PubMed Publications
 Cxcr4 sirna  >2 publications with HEBP1 and Cxcr4
 Cxcl12 sirna  >1 publications with HEBP1 and Cxcl12
 Fpr3 sirna  >1 publications with HEBP1 and Fpr3
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with HEBP1 sirnaOrgans/Tissues associated with HEBP1 sirna
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >653 publications with HEBP1 and Inflammation
 Disease Models, Animal Antibodies  >390 publications with HEBP1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >369 publications with HEBP1 and Nervous System Diseases
 Necrosis Antibodies  >299 publications with HEBP1 and Necrosis
 Liver Diseases Antibodies  >287 publications with HEBP1 and Liver Diseases
 Brain Diseases Antibodies  >263 publications with HEBP1 and Brain Diseases
 Adenocarcinoma Antibodies  >130 publications with HEBP1 and Adenocarcinoma
 Kidney Diseases Antibodies  >129 publications with HEBP1 and Kidney Diseases
 Drug-Induced Liver Injury Antibodies  >127 publications with HEBP1 and Drug-Induced Liver Injury
 Fibrosis Antibodies  >119 publications with HEBP1 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >625 publications with HEBP1 and Liver
 Lung Antibodies  >423 publications with HEBP1 and Lung
 Brain Antibodies  >386 publications with HEBP1 and Brain
 Muscle Antibodies  >231 publications with HEBP1 and Muscle
 Kidney Antibodies  >225 publications with HEBP1 and Kidney
 Heart Antibodies  >209 publications with HEBP1 and Heart
 Skin Antibodies  >129 publications with HEBP1 and Skin
 Intestine Antibodies  >90 publications with HEBP1 and Intestine
 Embryonic Tissue Antibodies  >39 publications with HEBP1 and Embryonic Tissue
 Stomach Antibodies  >34 publications with HEBP1 and Stomach
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