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LANCL1 sirna

Scan QR to view Datasheet Catalog #    MBS8232716 LANCL1 sirna
Unit / Price
15 nmol  /  $365 +1 FREE 8GB USB
30 nmol  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LANCL1, siRNA

 Also Known As   

LANCL1 siRNA (Rat)

 Product Synonym Names    GPR69A; LanC-like protein 1; 40 kDa erythrocyte membrane protein; p40
 Product Gene Name   

LANCL1 sirna

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9QX69
 Host    Synthetic
 Species Reactivity    Rat
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 Specificity    LANCL1 siRNA (Rat) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
 Purity/Purification    > 97%
 Form/Format    Lyophilized powder
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 Quality Control    Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
 Directions for Use    We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
 Components    We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of rat LANCL1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Negative Control    siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
 Other Notes    Small volumes of LANCL1 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for LANCL1 sirna

   siRNA to inhibit LANCL1 expression using RNA interference
 Applications Tested/Suitable for LANCL1 sirna   

RNA Interference (RNAi)

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NCBI/Uniprot data below describe general gene information for LANCL1. It may not necessarily be applicable to this product.
 NCBI GI #    39930499
 NCBI GeneID    114515
 NCBI Accession #    NP_446175.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_053723.1 [Other Products]
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 UniProt Primary Accession #    Q9QX69 [Other Products]
 UniProt Secondary Accession #    Q9ER29 [Other Products]
 UniProt Related Accession #    Q9QX69 [Other Products]
 Molecular Weight    45,240 Da
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 NCBI Official Full Name    lanC-like protein 1
 NCBI Official Synonym Full Names    LanC lantibiotic synthetase component C-like 1 (bacterial)
 NCBI Official Symbol    Lancl1 [Similar Products]
 NCBI Official Synonym Symbols   
p40; GPR69A
[Similar Products]
 NCBI Protein Information    lanC-like protein 1
 UniProt Protein Name    LanC-like protein 1
 UniProt Synonym Protein Names   
40 kDa erythrocyte membrane protein; p40
 Protein Family    LanC-like protein
 UniProt Gene Name    Lancl1 [Similar Products]
 UniProt Synonym Gene Names    Gpr69a; p40 [Similar Products]
 UniProt Entry Name    LANC1_RAT
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 NCBI Summary for LANCL1    peptide-modifying enzyme; may be involved in modification and transport of antimicrobial peptides [RGD, Feb 2006]
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 UniProt Comments for LANCL1    LANCL1: May play a role in EPS8 signaling. Binds glutathion. Belongs to the LanC-like protein family.

Protein type: Receptor, misc.

Cellular Component: integral to plasma membrane; cytoplasm; nucleus

Molecular Function: glutathione binding; low-density lipoprotein receptor binding; zinc ion binding; SH3 domain binding; catalytic activity

Biological Process: G-protein coupled receptor protein signaling pathway; metabolic process
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 Research Articles on LANCL1    1. Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to LANCL1 siRNA (Rat)
 Catalog #  Product Name  Catalog #  Product Name
 MBS7048554  LANCL1 Antibody, FITC conjugated  MBS7048555  LANCL1 Antibody, Biotin conjugated
 MBS7048553  LANCL1 Antibody, HRP conjugated  MBS7600924  LANCL1 Rabbit Polyclonal
 MBS8232716  LANCL1 siRNA (Rat)  MBS205527  LANCL1, 1-399aa, Human, His tag, E Coli
 MBS2521322  LANCL1 Antibody  MBS416094  Anti-LANCL1 Antibody
 MBS9401143  LANCL1 Antibody  MBS1270136  LANCL1 cDNA Clone
Products associated with LANCL1 sirnaDiseases associated with LANCL1 sirna
 Reference Product  PubMed Publications
 Eps8 sirna  >1 publications with LANCL1 and Eps8
 Cbs sirna  >1 publications with LANCL1 and Cbs
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with LANCL1 and Breast Neoplasms
 Inflammation Antibodies  >1 publications with LANCL1 and Inflammation
Organs/Tissues associated with LANCL1 sirna
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with LANCL1 and Brain
 Testis Antibodies  >5 publications with LANCL1 and Testis
 Nerve Antibodies  >2 publications with LANCL1 and Nerve
 Colon Antibodies  >2 publications with LANCL1 and Colon
 Eye Antibodies  >1 publications with LANCL1 and Eye
 Kidney Antibodies  >1 publications with LANCL1 and Kidney
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