NP_001258636.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,985 Da
NCBI Official Full Name
probable E3 ubiquitin-protein ligase makorin-2 isoform 2
NCBI Official Synonym Full Names
makorin ring finger protein 2
NCBI Protein Information
probable E3 ubiquitin-protein ligase makorin-2
UniProt Protein Name
Probable E3 ubiquitin-protein ligase makorin-2
UniProt Synonym Protein Names
RING finger protein 62
UniProt Synonym Gene Names
UniProt Entry Name
MKRN2_HUMAN
NCBI Summary for MKRN2
This gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) gene in an antisense orientation and may have a co-regulatory function with RAF1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
UniProt Comments for MKRN2
MKRN2: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Protein type: Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 3p25
Cellular Component: intracellular
Molecular Function: protein binding; zinc ion binding; ligase activity
Biological Process: protein ubiquitination
Research Articles on MKRN2
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Products associated with MKRN2 sirna
Diseases associated with MKRN2 sirna
Organs/Tissues associated with MKRN2 sirna
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